Journal of Rheumatic Diseases

Table. 1.

Characteristics of HPV-B19 infection versus SLE

Clinical/Laboratory features HPV-B19 infection SLE
Clinical features
Duration Transient Chronic
Severity Mild Mild to severe
Malar rash + +
Arthralgia/arthritis + +
Fever + +
Fatigue + +
Myalgia + +
Oral ulcer Rare +
Serositis Rare +
Organ involvement (heart, kidney, spleen, eye, GI, CNS) Rare +
Discoid rash +
Alopecia +
Raynaud’s phenomenon +
Laboratory features
Hypocomplementemia + +
Elevated ESR + +
Positive Coomb’s test + +
Leukopenia + +
Thrombocytopenia + +
Anemia Due to bone- marrow suppression Due to chronic disease or autoimmune hemolysis
Autoantibodies (ANA, anti-dsDNA Ab, anti-cardiolipin Ab, anti-β2 glycoprotein Ab, Anti-SSA/Ro Ab, anti-SSB/La Ab, rheumatoid factor) Transient Persistent

HPV-B19: Human parvovirus B19, SLE: systemic lupus erythematosus, GI: gastrointestinal tract, CNS: central nervous system, ESR: erythrocyte sedimentation rate, ANA: antinuclear antibody, anti-dsDNA: anti-double stranded DNA, Ab: antibody. +: present, −: absent.

J Rheum Dis 2021;28:45~49 https://doi.org/10.4078/jrd.2021.28.1.45
© J Rheum Dis