Journal of Rheumatic Diseases

Table. 5.

Interactions with baseline characteristics and spinal radiographic progression with generalized estimating equations model among male patients with ankylosing spondylitis (n=85)

Variable Univariate analysis Multivariable analysis


β (95% CI) p-value β (95% CI) p-value
Time 1.78 (1.10∼2.46) <0.001 −1.57 (−5.03∼1.90) 0.375
Time*current smoker −0.414 (−1.73∼0.90) 0.539
Time*uveitis 0.04 (−1.32∼1.40) 0.954
Time*enthesitis −1.02 (−1.87∼−0.17) 0.018 0.19 (−0.57∼0.95) 0.619
Time*peripheral arthritis −1.31 (−2.46∼−0.17) 0.025 −0.34 (−1.23∼0.56) 0.459
Time*hip arthritis −0.38 (−1.83∼1.08) 0.612
Time*leptin/100 0.00 (0.00∼0.01) 0.383
Time*Dkk1/100 −0.13 (−0.20∼−0.05) 0.001 −0.10 (−0.15∼−0.04) 0.001
Time*estrogen −0.01 (−0.03∼0.01) 0.272
Time*age at symptom onset 0.08 (0.02∼0.13) 0.004 0.03 (−0.01∼0.08) 0.109
Time*initial ESR 0.01 (−0.01∼0.03) 0.468
Time*initial CRP 0.22 (0.07∼0.38) 0.005 0.11 (0.00∼0.23) 0.050
Time*BMI 0.19 (0.03∼0.36) 0.021 0.13 (0.01∼0.26) 0.039
Time*initial mSASSS 0.03 (−0.02∼0.08) 0.189 0.21 (0.02∼0.40) 0.030

Dkk1: dickkopf-1, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein, BMI: body mass index, mSASSS: modified Stoke Ankylosing Spondylitis Spine Score, CI: confidence interval.

J Rheum Dis 2021;28:76~84 https://doi.org/10.4078/jrd.2021.28.2.76
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