Journal of Rheumatic Diseases

Table. 3.

Linear regression of continuous variables based on the BVAS in AAV patients

Variables Univariable Multivariable


Standardised correlation coefficient (β) p-value Standardised correlation coefficient (β) 95% confidence interval p-value
CH50 (U/mL) −0.241 0.015 −0.265 −0.173 to −0.036 0.003
C3 (mg/dL) −0.015 0.884
C4 (mg/dL) −0.140 0.175
Age (yr) 0.101 0.314
White blood cell count (/mm3) 0.198 0.047 0.032 0.000 to 0.000 0.791
Haemoglobin (g/dL) −0.500 <0.001 −0.374 −1.842 to −0.261 0.010
Platelet count (×1,000/mm3) 0.262 0.008 0.106 −0.006 to 0.015 0.402
Fasting glucose (mg/dL) −0.033 0.741
Blood urea nitrogen (mg/dL) 0.286 0.004 0.059 −0.054 to 0.098 0.575
Serum creatinine (mg/dL) 0.179 0.074
Total protein (g/dL) 0.035 0.731
Serum albumin (g/dL) −0.440 <0.001 −0.021 −2.951 to 2.591 0.898
Alkaline phosphatase (IU/L) 0.225 0.025 0.185 −0.004 to 0.061 0.084
Aspartate aminotransferase (IU/L) −0.120 0.234
Alanine aminotransferase (IU/L) −0.228 0.022 −0.093 −0.116 to 0.047 0.399
Total bilirubin (mg/dL) −0.151 0.135
ESR (mm/hr) 0.327 0.001 0.175 −0.014 to 0.075 0.180
CRP (mg/L) 0.237 0.017 −0.132 −0.049 to 0.020 0.401

BVAS: Birmingham Vasculitis Activity Score, AAV: ANCA-associated vasculitis, ANCA: antineutrophil cytoplasmic antibody, CH50: total haemolytic complement activity, C3: complement 3, C4: complement 4, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein.

J Rheum Dis 2021;28:85~93 https://doi.org/10.4078/jrd.2021.28.2.85
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