J Rheum Dis 2017; 24(4): 174-184  
Renal Involvement in Rheumatic Diseases
Seon-Ho Ahn, Jong Hwan Jung
Division of Nephrology, Department of Internal Medicine, Wonkwang University School of Medicine and Hospital, Iksan, Korea
Correspondence to: Jong Hwan Jung, Division of Nephrology, Department of Internal Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan 54538, Korea. E-mail:chjh0502@wku.ac.kr
Received: April 10, 2017; Revised: May 8, 2017; Accepted: May 11, 2017; Published online: August 31, 2017.
© Korean College of Rheumatology. All rights reserved.

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Abstract
Most rheumatic diseases are chronic inflammatory diseases. Kidney-related symptoms of rheumatic diseases are often present, which increase mortality and morbidity of patients with rheumatic diseases. When patients with rheumatic diseases show signs or symptoms of renal involvement, management for primary rheumatic diseases should be more aggressive. In general, the risk and severity of renal involvement in patients with rheumatic diseases depend on the type of primary rheumatic diseases. Rheumatic disease itself, chronic use of immunosuppressive agents and non-steroidal anti-inflammatory drugs, and comorbidities, such as diabetes, hypertension, and cardiovascular complications, are the main causes of renal involvement in patients with rheumatic diseases. Many studies have reported the predominant features of renal involvement in most rheumatic diseases. We have attempted to summarize the relationships between rheumatic diseases and renal diseases, and clinical or pathophysiological features of renal involvement resulting from primary rheumatic diseases except systemic lupus erythematosus. Review for renal involvement, particularly in relation to early diagnosis and management of renal involvement in rheumatic diseases, is clinically significant because renal involvement in rheumatic diseases generally implies a bad prognosis.
Keywords: Kidney diseases, Rheumatic diseases, Inflammation


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