J Rheum Dis 2017; 24(5): 303-308  
Focal Eosinophilic Myositis Associated with Behçet's Disease
Jung Su Eun1, Jong Wan Kang1, Jin Young Kang2, Na Ri Kim1, Sang Jin Lee1, Young Mo Kang1, Man Hoon Han3, Eon Jeong Nam1
1Division of Rheumatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, 2Division of Rheumatology, Department of Internal Medicine, Changwon Fatima Hospital, Changwon, 3Department of Pathology, Kyungpook National University School of Medicine, Daegu, Korea
Correspondence to: Eon Jeong Nam, Division of Rheumatology, Department of Internal Medicine, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu 41944, Korea. E-mail:ejnam@knu.ac.kr
Received: March 21, 2017; Revised: April 12, 2017; Accepted: April 19, 2017; Published online: October 31, 2017.
© Korean College of Rheumatology. All rights reserved.

This is a open Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Behçet’s disease (BD) is a systemic vasculitis commonly accompanied by recurrent mucosal ulceration and other systemic manifestations, but rarely by myositis. Focal eosinophilic myositis is the most limited idiopathic eosinophilic myopathy characterized by peripheral blood eosinophilia and/or eosinophilic muscle infiltration. Clinical manifestations include myalgia, muscle weakness, and cutaneous lesions, such as subcutaneous induration and erythema. Given that BD can mimic deep vein thrombosis or pseudotumor, muscle biopsy should be performed to enhance the accuracy of diagnosis. Microscopic examination reveals extensive infiltration of eosinophils and mononuclear cells into muscle, myofiber necrosis, and regeneration. To the best of our knowledge, there have not been any published reports on MEDLINE regarding focal eosinophilic myositis associated with BD. Here, we presented a case of focal eosinophilic myositis associated with intestinal BD in a 23-year-old man who suffered from a large ulcer in the terminal ileum.
Keywords: Behçet’s disease, Idiopathic eosinophilic myopathy, Focal eosinophilic myositis


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