J Rheum Dis 2019; 26(2): 93-103  
Psychiatric Symptoms in Systemic Lupus Erythematosus: Diagnosis and Treatment
Seoyoung Yoon, Dae Hun Kang, Tae Young Choi
Department of Psychiatry, Catholic University of Daegu School of Medicine, Daegu, Korea
Correspondence to: Tae Young Choi http://orcid.org/0000-0003-2677-9297
Department of Psychiatry, Catholic University of Daegu School of Medicine, 33 Duryugongwon-ro 17-gil, Nam-gu, Daegu 42472, Korea. E-mail:tyoungchoi@cu.ac.kr
Received: December 8, 2018; Revised: January 8, 2019; Accepted: January 22, 2019; Published online: April 1, 2019.
© Korean College of Rheumatology. All rights reserved.

This is a open Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
According to the American College of Rheumatology classification, lupus erythematosus has five psychiatric manifestations, including cognitive dysfunction, mood disorder, anxiety disorder, psychosis, and acute confusional state, which are frequently accompanied by other symptoms. Cognitive dysfunction is the most common psychiatric manifestation in lupus patients with a prevalence rate ranging from 20% to 80%. The expression of psychiatric manifestations has been considered to be associated with disease activity, side effects of medications, and/or psychosocial stresses from the chronicity of lupus, but this has not been fully understood. Appropriate management of psychiatric symptoms is essential as it affects treatment adherence and quality of life. This review aimed to facilitate understanding of psychiatric manifestations of lupus through literature review on the prevalence, clinical features, diagnosis, and treatments of each psychiatric symptom.
Keywords: Lupus erythematosus, systemic, Mental disorders, Diagnosis, Therapeutics


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