Journal of Rheumatic Diseases

Table. 1.

The MR estimates from each method of assessing the causal effect of years of education on the risk of RA

MR method Number of SNPs Beta SE Association p-value Cochran Q statistic Heterogeneity p-value
Inverse variance weighted 49 −0.754 0.283 0.008 81.03 0.002
MR Egger 49 −2.320 1.709 0.181 79.56 0.002
Weighted median 49 −0.950 0.355 0.008 80.75* 0.002*

MR: Mendelian randomization, RA: rheumatoid arthritis, SNP: single nucleotide polymorphism, Beta: beta coefficient, SE: standard error. *Maximum likelihood method

J Rheum Dis 2020;27:241~246 https://doi.org/10.4078/jrd.2020.27.4.241
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