Journal of Rheumatic Diseases

Table. 3.

Serum TNF-α, IL-6, MMP-7, SP-D, and KL-6 levels according to semiquantitative CT grades

Grade 1 (n=86) Grade 2 (n=46) Grade 3 (n=15) Grade 4 (n=6) p-value
TNF-α (pg/mL) 3.26±8.46 4.35±9.98 2.55±5.69 1.72±0.67 0.674
IL-6 (pg/mL) 4.50±13.69 10.33±40.13 3.43±3.72 3.16±2.03 0.282
MMP-7 (pg/mL) 6,885.47±3,890.06 8,074.50±5,342.70 8,361.50±4,730.29 10,396.35±3,465.75 0.013
SP-D (pg/mL) 8,422.91±6,899.35 10,399.37±6,518.88 12,472.11±7,794.94 16,264.79±9,174.95 <0.001
KL-6 (units/mL) 485.84±471.36 675.98±385.39 824.20±1016.52 1,051.10±612.84 <0.001

Values are presented as mean±standard deviation. TNF-α: tumor necrosis factor α, IL-6: interleukin 6, MMP-7: matrix metallopeptidase 7, SP-D: surfactant protein D, KL-6: Krebs von den Lungen 6, CT: computed tomography.

J Rheum Dis 2021;28:234~241 https://doi.org/10.4078/jrd.2021.28.4.234
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