Journal of Rheumatic Diseases

Table. 2.

Univariable Cox hazards model analysis of variables at diagnosis for predicting all-cause mortality in AAV patients

Variables Univariable
HR 95% CI p-value
Age (yr) 1.052 1.016~1.090 0.005
Male sex 1.728 0.782~3.820 0.176
MPO-ANCA (or P-ANCA) positivity 1.469 0.623~3.464 0.380
PR3-ANCA (or C-ANCA) positivity 0.961 0.357~2.585 0.937
BVAS 1.101 1.046~1.159 <0.001
FFS 2.752 1.783~4.246 <0.001
Chronic kidney disease (stages 3~5) 2.269 1.032~4.988 0.041
Diabetes mellitus 0.854 0.341~2.143 0.737
Hypertension 1.160 0.526~2.557 0.713
Interstitial lung disease 2.546 1.151~5.630 0.021
ESR 1.004 0.994~1.014 0.395
CRP 1.007 1.001~1.013 0.017
BMI 1.070 0.920~1.244 0.382
Serum albumin 0.308 0.175~0.544 <0.001
mBMI 0.996 0.994~0.998 0.001

AAV: ANCA-associated vasculitis, ANCA: antineutrophil cytoplasmic antibody, HR: hazard ratio, CI: confidence interval, MPO: myeloperoxidase, P: perinuclear, PR3: proteinase 3, C: cytoplasmic, BVAS: Birmingham vasculitis activity score, FFS: five factor score, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein: BMI: body mass index, mBMI: modified body mass index.

J Rheum Dis 2022;29:154~161 https://doi.org/10.4078/jrd.2022.29.3.154
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