J Rheum Dis
Published online September 4, 2024
© Korean College of Rheumatology
Correspondence to : Hyoun-Ah Kim, https://orcid.org/0000-0003-2609-3367
Department of Rheumatology, Ajou University School of Medicine, 164 Worldcup-ro, Yeongtong-gu, Suwon 16499, Korea.
E-mail: nakhada@ajou.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: Pain is a significant and debilitating symptom of rheumatoid arthritis (RA) that significantly affects the quality of life and functional ability of patients. In the present study, we examined the association between pain variables and disease activity markers in patients with RA.
Methods: We enrolled 133 patients with RA and assessed their clinical characteristics, socioeconomic and psychological factors, and pain measures. The psychological factors assessed included depressive symptoms and pain catastrophizing.
Results: The study cohort comprised predominantly female patients with RA with an average age of 55.5±10.1 years. Depressive symptoms had a mean score of 5.83±4.71, while pain catastrophizing had an average score of 14.36±10.70. The mean scores for pain intensity, and pain interference, were 2.98±1.75 and 19.54±16.17, respectively, with significant positive correlations observed with depressive symptoms. Hemoglobin and hematocrit levels were negatively correlated with pain intensity. Multivariable linear regression analysis revealed significant associations between depressive symptoms and pain intensity, catastrophizing, and interference. Other factors associated with pain intensity included tender joint count. Pain catastrophizing was associated with education and economic status. Pain interference was associated with sex and economic status.
Conclusion: This study shows the influence of disease-related indicators and psychological factors on pain in patients with RA, with depressive symptoms playing a crucial role in predicting pain experience. Effective pain management strategies for RA should include the management of depressive symptoms, in addition to addressing disease-related indicators.
Keywords Rheumatoid arthritis, Pain intensity, Pain interference, Pain catastrophizing, Depression
J Rheum Dis
Published online September 4, 2024
Copyright © Korean College of Rheumatology.
Hee Jun Kim, R.N., Ph.D.1 , Ju-Yang Jung, M.D., Ph.D.2 , Ji-Won Kim, M.D.2 , Chang-Hee Suh, M.D., Ph.D.2 , Hyoun-Ah Kim, M.D., Ph.D.2
1School of Nursing, The George Washington University, Washington, DC, USA, 2Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea
Correspondence to:Hyoun-Ah Kim, https://orcid.org/0000-0003-2609-3367
Department of Rheumatology, Ajou University School of Medicine, 164 Worldcup-ro, Yeongtong-gu, Suwon 16499, Korea.
E-mail: nakhada@ajou.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: Pain is a significant and debilitating symptom of rheumatoid arthritis (RA) that significantly affects the quality of life and functional ability of patients. In the present study, we examined the association between pain variables and disease activity markers in patients with RA.
Methods: We enrolled 133 patients with RA and assessed their clinical characteristics, socioeconomic and psychological factors, and pain measures. The psychological factors assessed included depressive symptoms and pain catastrophizing.
Results: The study cohort comprised predominantly female patients with RA with an average age of 55.5±10.1 years. Depressive symptoms had a mean score of 5.83±4.71, while pain catastrophizing had an average score of 14.36±10.70. The mean scores for pain intensity, and pain interference, were 2.98±1.75 and 19.54±16.17, respectively, with significant positive correlations observed with depressive symptoms. Hemoglobin and hematocrit levels were negatively correlated with pain intensity. Multivariable linear regression analysis revealed significant associations between depressive symptoms and pain intensity, catastrophizing, and interference. Other factors associated with pain intensity included tender joint count. Pain catastrophizing was associated with education and economic status. Pain interference was associated with sex and economic status.
Conclusion: This study shows the influence of disease-related indicators and psychological factors on pain in patients with RA, with depressive symptoms playing a crucial role in predicting pain experience. Effective pain management strategies for RA should include the management of depressive symptoms, in addition to addressing disease-related indicators.
Keywords: Rheumatoid arthritis, Pain intensity, Pain interference, Pain catastrophizing, Depression
In-Woon Baek, M.D., Kyung-Su Park, M.D., Ph.D., Ki-Jo Kim, M.D., Ph.D.
J Rheum Dis -0001; ():Wan Kee Hong, M.D., Joong Mo Ahn, M.D., Ph.D., Hyun Sik Gong, M.D., Ph.D.
J Rheum Dis -0001; ():Young Ho Lee, M.D., Ph.D., Jae-Bum Jun, M.D., Ph.D.
J Rheum Dis -0001; ():