Case Report

J Rheum Dis 2013; 20(3): 190-193

Published online June 30, 2013

© Korean College of Rheumatology

다발성 피부 병변을 보인 류마티스관절염 환자의 Sweet 증후군 1예

서영호ㆍ이영호ㆍ지종대ㆍ송관규ㆍ유서희ㆍ안젬마ㆍ최성재

고려대학교 의과대학 내과학교실 류마티스내과

A Case of Sweet's Syndrome Associated with Rheumatoid Arthritis Involving Multiple Skin Lesions

Young Ho Seo, Young Ho Lee, Jong Dae Ji, Gwan Gyu Song, Seu Hee Yoo, Jemma Ahn, Sung Jae Choi

Division of Rheumatology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea

Correspondence to : Sung Jae Choi

Abstract

Sweet's syndrome is a neutrophilic dermatoses characterized by the abrupt onset of fever, leukocytosis and skin lesions that are infiltrated by neutrophils. Most skin lesions are in the form of erythematous tender papules or nodules, usually affecting the upper limbs, face or neck and histologically a dense perivascular infiltrate of neutrophils without vasculitis. Sweet's syndrome can be associated with several disorders, such as inflammatory bowel disease, malignant tumors, and autoimmune diseases including rheumatoid arthritis. We report a case of Sweet's syndrome with associated rheumatoid arthritis. The patient had multiple skin lesions in her face, neck, both upper and lower extremities except trunk, and complained fever, chills and arthralgia. The result of skin biopsy showed mature neutriphil infiltration and leukocytoclasia of dermis without vasculitis, which was compatible with Sweet's syndrome.

Keywords Sweet's syndrome, Rheumatoid arthritis

Article

Case Report

J Rheum Dis 2013; 20(3): 190-193

Published online June 30, 2013

Copyright © Korean College of Rheumatology.

다발성 피부 병변을 보인 류마티스관절염 환자의 Sweet 증후군 1예

서영호ㆍ이영호ㆍ지종대ㆍ송관규ㆍ유서희ㆍ안젬마ㆍ최성재

고려대학교 의과대학 내과학교실 류마티스내과

A Case of Sweet's Syndrome Associated with Rheumatoid Arthritis Involving Multiple Skin Lesions

Young Ho Seo, Young Ho Lee, Jong Dae Ji, Gwan Gyu Song, Seu Hee Yoo, Jemma Ahn, Sung Jae Choi

Division of Rheumatology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea

Correspondence to:Sung Jae Choi

Abstract

Sweet's syndrome is a neutrophilic dermatoses characterized by the abrupt onset of fever, leukocytosis and skin lesions that are infiltrated by neutrophils. Most skin lesions are in the form of erythematous tender papules or nodules, usually affecting the upper limbs, face or neck and histologically a dense perivascular infiltrate of neutrophils without vasculitis. Sweet's syndrome can be associated with several disorders, such as inflammatory bowel disease, malignant tumors, and autoimmune diseases including rheumatoid arthritis. We report a case of Sweet's syndrome with associated rheumatoid arthritis. The patient had multiple skin lesions in her face, neck, both upper and lower extremities except trunk, and complained fever, chills and arthralgia. The result of skin biopsy showed mature neutriphil infiltration and leukocytoclasia of dermis without vasculitis, which was compatible with Sweet's syndrome.

Keywords: Sweet's syndrome, Rheumatoid arthritis

JRD
Oct 01, 2024 Vol.31 No.4, pp. 191~263
COVER PICTURE
Ancestry-driven pathways for SLE-risk SNP-associated genes. The ancestry-driven key signaling pathways in Asians, Europeans, and African Americans were analyzed by enrichr (https://maayanlab.cloud/Enrichr/#libraries) using non-HLA SNP-associated genes. SLE: systemic lupus erythematosus, SNP: single-nucleotide polymorphism, JAK–STAT: janus kinase–signal transducers and activators of transcription, IFN: interferon gamma. (J Rheum Dis 2024;31:200-211)

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