Case Report

J Rheum Dis 2013; 20(4): 251-255

Published online August 30, 2013

© Korean College of Rheumatology

상부 인두근육을 침범한 류마티스관절염과 다발성 근염이 합병된 중복 증후군 1예

장원석ㆍ김소미ㆍ홍승재ㆍ이상훈ㆍ송란ㆍ양형인ㆍ이연아

A Case of Overlap Syndrome of Rheumatoid Arthritis and Polymyositis with the Involvement of Upper Pharyngeal Muscles

Won Seok Jang, So-Mi Kim, Seung-Jae Hong, Sang-Hoon Lee, Ran-Song, Hyung-In Yang, Yeon-Ah Lee

Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, Korea

Correspondence to : Yeon-Ah Lee

Abstract

An overlap syndrome is a combination of major features of more than one connective tissue diseases which is pre-sented in the same patient. An overlap syndrome of rheu-matoid arthritis (RA) and polymyositis (PM) which in-volved the upper pharyngeal muscle has not been reported in Korea. Herein, we report a rare case of a patient with a long-history RA presenting proximal muscle weakness and swallowing difficulty, who was successfully treated with a high-dose of corticosteroid, azathioprine and tacrolimus.

Keywords Rheumatoid arthritis, Polymyositis, Overlap syndrome

Article

Case Report

J Rheum Dis 2013; 20(4): 251-255

Published online August 30, 2013

Copyright © Korean College of Rheumatology.

상부 인두근육을 침범한 류마티스관절염과 다발성 근염이 합병된 중복 증후군 1예

장원석ㆍ김소미ㆍ홍승재ㆍ이상훈ㆍ송란ㆍ양형인ㆍ이연아

A Case of Overlap Syndrome of Rheumatoid Arthritis and Polymyositis with the Involvement of Upper Pharyngeal Muscles

Won Seok Jang, So-Mi Kim, Seung-Jae Hong, Sang-Hoon Lee, Ran-Song, Hyung-In Yang, Yeon-Ah Lee

Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, Korea

Correspondence to:Yeon-Ah Lee

Abstract

An overlap syndrome is a combination of major features of more than one connective tissue diseases which is pre-sented in the same patient. An overlap syndrome of rheu-matoid arthritis (RA) and polymyositis (PM) which in-volved the upper pharyngeal muscle has not been reported in Korea. Herein, we report a rare case of a patient with a long-history RA presenting proximal muscle weakness and swallowing difficulty, who was successfully treated with a high-dose of corticosteroid, azathioprine and tacrolimus.

Keywords: Rheumatoid arthritis, Polymyositis, Overlap syndrome

JRD
Oct 01, 2024 Vol.31 No.4, pp. 191~263
COVER PICTURE
Ancestry-driven pathways for SLE-risk SNP-associated genes. The ancestry-driven key signaling pathways in Asians, Europeans, and African Americans were analyzed by enrichr (https://maayanlab.cloud/Enrichr/#libraries) using non-HLA SNP-associated genes. SLE: systemic lupus erythematosus, SNP: single-nucleotide polymorphism, JAK–STAT: janus kinase–signal transducers and activators of transcription, IFN: interferon gamma. (J Rheum Dis 2024;31:200-211)

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