J Rheum Dis 2013; 20(5): 328-331
Published online October 30, 2013
© Korean College of Rheumatology
지용관ㆍ라상호ㆍ박유미ㆍ차재황ㆍ강용석ㆍ박정하ㆍ강태영
연세대학교 원주의과대학 내과학교실
Correspondence to : Jeong Ha Park
We describe a 48-year-old man with family history of rheumatoid arthritis (RA) affected by chronic eosinophilic pneumonia (CEP) with severe peripheral eosinophilia. CEP might develop as a complication of longstanding ac-tive RA. The patient with 5 months history of seropositive RA and chronic respiratory symptoms, alveolar and blood eosinophilia, peripheral pulmonary infiltrates and pleural effusion on chest imaging. The lung may be involved as an extraarticular manifestation of RA. However, CEP is not recognized as a typical lung manifestation of RA, and the two diseases rarely coexist. The effusion was an eosino-phil predominant exudates and was characterized by low pH, and glucose level and high lactic dehydrogenase. The patient responded rapidly to combination of steroids and disease modifying anti-rheumatic drugs.
Keywords Rheumatoid arthritis, Chronic eosinophilic pneumonia, Pleural effusion
J Rheum Dis 2013; 20(5): 328-331
Published online October 30, 2013
Copyright © Korean College of Rheumatology.
지용관ㆍ라상호ㆍ박유미ㆍ차재황ㆍ강용석ㆍ박정하ㆍ강태영
연세대학교 원주의과대학 내과학교실
Yong Gwan Jee, Sang Ho Ra, Yu Mi Park, Jae Whang Cha, Yong Seok Kang, Jeong Ha Park, Tae Young Kang
Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
Correspondence to:Jeong Ha Park
We describe a 48-year-old man with family history of rheumatoid arthritis (RA) affected by chronic eosinophilic pneumonia (CEP) with severe peripheral eosinophilia. CEP might develop as a complication of longstanding ac-tive RA. The patient with 5 months history of seropositive RA and chronic respiratory symptoms, alveolar and blood eosinophilia, peripheral pulmonary infiltrates and pleural effusion on chest imaging. The lung may be involved as an extraarticular manifestation of RA. However, CEP is not recognized as a typical lung manifestation of RA, and the two diseases rarely coexist. The effusion was an eosino-phil predominant exudates and was characterized by low pH, and glucose level and high lactic dehydrogenase. The patient responded rapidly to combination of steroids and disease modifying anti-rheumatic drugs.
Keywords: Rheumatoid arthritis, Chronic eosinophilic pneumonia, Pleural effusion
Byeongzu Ghang, M.D., Ph.D., Jin Kyun Park, M.D., Ph.D., Ji Hyeon Ju, M.D., Ph.D., Seungwoo Han, M.D., Ph.D.
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