Case Report
J Rheum Dis 2014; 21(6): 336-339
Published online December 30, 2014
© Korean College of Rheumatology
Hemorrhagic Cystitis with Giant Cells in Rheumatoid Arthritis Treating with Tacrolimus
Correspondence to : Wan-Hee Yoo
Hemorrhagic cystitis is a diffuse inflammation of the mu-cosa of the bladder, characterized by hematuria and burn-ing upon urination. This might be caused by a variety of reasons, including undergoing chemotherapy (such as cy-clophosphamide), radiation therapy, bladder cancer, cer-tain viruses, urinary infections, and thrombocytopenia. There are no previous reports of hemorrhagic cystitis asso-ciated with the use of tacrolimus. This is the first case of hemorrhagic cystitis due to tacrolimus for the treatment of rheumatoid arthritis. We describe a case of hemor-rhagic cystitis with giant cells in a patient with rheumatoid arthritis treating with tacrolimus. Hematuria resolved spontaneously with discontinuation of the drug.
Keywords Hemorrhagic cystitis, Rheumatoid arthritis, Tacrolimus
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Case Report
J Rheum Dis 2014; 21(6): 336-339
Published online December 30, 2014
Copyright © Korean College of Rheumatology.
Hemorrhagic Cystitis with Giant Cells in Rheumatoid Arthritis Treating with Tacrolimus
In Suk Min, YeonMi Ju, Hyun-young Kim, Yun Jung Choi, Won-Seok Lee, Wan-Hee Yoo
Department of Rheumatology, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, Jeonju, Korea
Correspondence to:Wan-Hee Yoo
Abstract
Hemorrhagic cystitis is a diffuse inflammation of the mu-cosa of the bladder, characterized by hematuria and burn-ing upon urination. This might be caused by a variety of reasons, including undergoing chemotherapy (such as cy-clophosphamide), radiation therapy, bladder cancer, cer-tain viruses, urinary infections, and thrombocytopenia. There are no previous reports of hemorrhagic cystitis asso-ciated with the use of tacrolimus. This is the first case of hemorrhagic cystitis due to tacrolimus for the treatment of rheumatoid arthritis. We describe a case of hemor-rhagic cystitis with giant cells in a patient with rheumatoid arthritis treating with tacrolimus. Hematuria resolved spontaneously with discontinuation of the drug.
Keywords: Hemorrhagic cystitis, Rheumatoid arthritis, Tacrolimus
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