Case Report
J Rheum Dis 2014; 21(1): 25-29
Published online February 28, 2014
© Korean College of Rheumatology
Acute Polymyositis/systemic Lupus Erythematosus Overlap Syndrome with Severe Subcutaneous Edema and Interstitial Lung Disease
Correspondence to : Hyoun-Ah Kim
Inflammatory myopathy is characterized by symmetrical proximal muscle weakness, elevated muscle enzyme levels and favorable response to glucocorticoids therapy. Although periorbital edema is a common manifestation of inflammatory myopathy, generalized subcutaneous edema is very rare. We report here a case of a 47-year-old female patient with acute polymyositis/systemic lupus eryth-ematosus overlap syndrome with generalized subcutaneous edema and interstitial lung disease. We aggressively treat-ed the disease with high-dose glucocorticoids, intravenous immunoglobulin, and immunosuppressive agents.
Keywords Inflammatory myopathy, Overlap syndrome, Subcutaneous edema, Interstitial lung disease
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Case Report
J Rheum Dis 2014; 21(1): 25-29
Published online February 28, 2014
Copyright © Korean College of Rheumatology.
Acute Polymyositis/systemic Lupus Erythematosus Overlap Syndrome with Severe Subcutaneous Edema and Interstitial Lung Disease
U-ram Jin1, Kyu-Sung Kwack2, Kyung-Joo Park2, Ji-Eun Kwon3, Si-Yeon Kim1, Ki-Chan Kim1, Ga-Yong Ban1, Ju-Yang Jung1, Chang-Hee Suh1, Hyoun-Ah Kim1
Departments of Rheumatology1, Radiology2, Pathology3, Ajou University School of Medicine, Suwon, Korea
Correspondence to:Hyoun-Ah Kim
Abstract
Inflammatory myopathy is characterized by symmetrical proximal muscle weakness, elevated muscle enzyme levels and favorable response to glucocorticoids therapy. Although periorbital edema is a common manifestation of inflammatory myopathy, generalized subcutaneous edema is very rare. We report here a case of a 47-year-old female patient with acute polymyositis/systemic lupus eryth-ematosus overlap syndrome with generalized subcutaneous edema and interstitial lung disease. We aggressively treat-ed the disease with high-dose glucocorticoids, intravenous immunoglobulin, and immunosuppressive agents.
Keywords: Inflammatory myopathy, Overlap syndrome, Subcutaneous edema, Interstitial lung disease
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