J Rheum Dis 2015; 22(1): 19-24
Published online February 28, 2015
© Korean College of Rheumatology
이상엽ㆍ임상우ㆍ박준용ㆍ정원태ㆍ이성원
동아대학교 의과대학 내과학교실 류마티스내과
Correspondence to : Sung Won Lee
Objective. This study was designed to assess sequential association between right ventricular systolic pressure and cardiothoracic (C/T) ratio of chest radiography in systemic sclerosis (SSc) patients and inferred pulmonary arterial hypertension by increased C/T ratio and right ventricular systolic pressure. Methods. Twenty-eight consecutive patients with confirmed SSc (22 females, 6 males; mean age 51.1±2.1 years), with a mean time of 91.0±6.7 months from SSc diagnosis, were prospectively included in the study. C/T ratio was obtained by chest radiography with an interval of two years. The first C/T ratio was taken at diagnosis and second C/T ratio was taken at the time of enrollment. The enrolled subjects were agree to undergo echocardiography and measurement of brain natriuretic peptide. Results. In 24 SSc patients with normal right ventricular systolic pressure, 10 SSc patients had increased C/T ratio, the other four SSc patients with increased right ventricular systolic pressure by echocardiography, had increased C/T ratio all together. In four SSc patients with increased right ventricular systolic pressure, one patient had resting dyspnea, taken cardiac catheterization and confirmed as pulmonary hypertension and the other three patients had no clinical symptoms. The increased right ventricular systolic pressure is related to the increase of C/T ratio (>0.55) in chest radiography (p<0.05) and increased brain natriuretic peptide in blood (p<0.05). Conclusion. The increase of C/T ratio (>0.55) in chest radiography was associated with increased right ventricular systolic pressure measured by echocardiography and inferred a role in early detection of asymptomatic pulmonary arterial hypertension in SSc patients. (J Rheum Dis 2015;22:19-24)
Keywords Pulmonary hypertension, Systemic sclerosis
J Rheum Dis 2015; 22(1): 19-24
Published online February 28, 2015
Copyright © Korean College of Rheumatology.
이상엽ㆍ임상우ㆍ박준용ㆍ정원태ㆍ이성원
동아대학교 의과대학 내과학교실 류마티스내과
Sang Yeob Lee, Sang Woo Yim, Jun Yong Park, Won Tae Chung, Sung Won Lee
Division of Rheumatology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea
Correspondence to:Sung Won Lee
Objective. This study was designed to assess sequential association between right ventricular systolic pressure and cardiothoracic (C/T) ratio of chest radiography in systemic sclerosis (SSc) patients and inferred pulmonary arterial hypertension by increased C/T ratio and right ventricular systolic pressure. Methods. Twenty-eight consecutive patients with confirmed SSc (22 females, 6 males; mean age 51.1±2.1 years), with a mean time of 91.0±6.7 months from SSc diagnosis, were prospectively included in the study. C/T ratio was obtained by chest radiography with an interval of two years. The first C/T ratio was taken at diagnosis and second C/T ratio was taken at the time of enrollment. The enrolled subjects were agree to undergo echocardiography and measurement of brain natriuretic peptide. Results. In 24 SSc patients with normal right ventricular systolic pressure, 10 SSc patients had increased C/T ratio, the other four SSc patients with increased right ventricular systolic pressure by echocardiography, had increased C/T ratio all together. In four SSc patients with increased right ventricular systolic pressure, one patient had resting dyspnea, taken cardiac catheterization and confirmed as pulmonary hypertension and the other three patients had no clinical symptoms. The increased right ventricular systolic pressure is related to the increase of C/T ratio (>0.55) in chest radiography (p<0.05) and increased brain natriuretic peptide in blood (p<0.05). Conclusion. The increase of C/T ratio (>0.55) in chest radiography was associated with increased right ventricular systolic pressure measured by echocardiography and inferred a role in early detection of asymptomatic pulmonary arterial hypertension in SSc patients. (J Rheum Dis 2015;22:19-24)
Keywords: Pulmonary hypertension, Systemic sclerosis
So-Young Yoon, Eun-Soo Yoo, Eun-Jung Yoo, Ju-Yang Jung, Hyoun-Ah Kim, Chang-Hee Suh
J Rheum Dis 2017; 24(2): 114-118Bong-Woo Lee, M.D., Eui-Jong Kwon, M.D., Ji Hyeon Ju, M.D., Ph.D.
J Rheum Dis -0001; ():Ha-Hee Son, M.D., Su-Jin Moon, M.D., Ph.D.
J Rheum Dis -0001; ():