Original Article

J Rheum Dis 2015; 22(1): 19-24

Published online February 28, 2015

© Korean College of Rheumatology

전신경화증에서 심장흉곽비와 수축기 우심실압 관계

이상엽ㆍ임상우ㆍ박준용ㆍ정원태ㆍ이성원

동아대학교 의과대학 내과학교실 류마티스내과

Received: September 4, 2014; Revised: November 5, 2014; Accepted: November 5, 2014

Correlation of Cardiothoracic Ratio and Right Ventricular Systolic Pressure in Systemic Sclerosis

Sang Yeob Lee, Sang Woo Yim, Jun Yong Park, Won Tae Chung, Sung Won Lee

Division of Rheumatology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea

Correspondence to : Sung Won Lee

Received: September 4, 2014; Revised: November 5, 2014; Accepted: November 5, 2014

Abstract

Objective. This study was designed to assess sequential association between right ventricular systolic pressure and cardiothoracic (C/T) ratio of chest radiography in systemic sclerosis (SSc) patients and inferred pulmonary arterial hypertension by increased C/T ratio and right ventricular systolic pressure. Methods. Twenty-eight consecutive patients with confirmed SSc (22 females, 6 males; mean age 51.1±2.1 years), with a mean time of 91.0±6.7 months from SSc diagnosis, were prospectively included in the study. C/T ratio was obtained by chest radiography with an interval of two years. The first C/T ratio was taken at diagnosis and second C/T ratio was taken at the time of enrollment. The enrolled subjects were agree to undergo echocardiography and measurement of brain natriuretic peptide. Results. In 24 SSc patients with normal right ventricular systolic pressure, 10 SSc patients had increased C/T ratio, the other four SSc patients with increased right ventricular systolic pressure by echocardiography, had increased C/T ratio all together. In four SSc patients with increased right ventricular systolic pressure, one patient had resting dyspnea, taken cardiac catheterization and confirmed as pulmonary hypertension and the other three patients had no clinical symptoms. The increased right ventricular systolic pressure is related to the increase of C/T ratio (>0.55) in chest radiography (p<0.05) and increased brain natriuretic peptide in blood (p<0.05). Conclusion. The increase of C/T ratio (>0.55) in chest radiography was associated with increased right ventricular systolic pressure measured by echocardiography and inferred a role in early detection of asymptomatic pulmonary arterial hypertension in SSc patients. (J Rheum Dis 2015;22:19-24)

Keywords Pulmonary hypertension, Systemic sclerosis

Article

Original Article

J Rheum Dis 2015; 22(1): 19-24

Published online February 28, 2015

Copyright © Korean College of Rheumatology.

전신경화증에서 심장흉곽비와 수축기 우심실압 관계

이상엽ㆍ임상우ㆍ박준용ㆍ정원태ㆍ이성원

동아대학교 의과대학 내과학교실 류마티스내과

Received: September 4, 2014; Revised: November 5, 2014; Accepted: November 5, 2014

Correlation of Cardiothoracic Ratio and Right Ventricular Systolic Pressure in Systemic Sclerosis

Sang Yeob Lee, Sang Woo Yim, Jun Yong Park, Won Tae Chung, Sung Won Lee

Division of Rheumatology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea

Correspondence to:Sung Won Lee

Received: September 4, 2014; Revised: November 5, 2014; Accepted: November 5, 2014

Abstract

Objective. This study was designed to assess sequential association between right ventricular systolic pressure and cardiothoracic (C/T) ratio of chest radiography in systemic sclerosis (SSc) patients and inferred pulmonary arterial hypertension by increased C/T ratio and right ventricular systolic pressure. Methods. Twenty-eight consecutive patients with confirmed SSc (22 females, 6 males; mean age 51.1±2.1 years), with a mean time of 91.0±6.7 months from SSc diagnosis, were prospectively included in the study. C/T ratio was obtained by chest radiography with an interval of two years. The first C/T ratio was taken at diagnosis and second C/T ratio was taken at the time of enrollment. The enrolled subjects were agree to undergo echocardiography and measurement of brain natriuretic peptide. Results. In 24 SSc patients with normal right ventricular systolic pressure, 10 SSc patients had increased C/T ratio, the other four SSc patients with increased right ventricular systolic pressure by echocardiography, had increased C/T ratio all together. In four SSc patients with increased right ventricular systolic pressure, one patient had resting dyspnea, taken cardiac catheterization and confirmed as pulmonary hypertension and the other three patients had no clinical symptoms. The increased right ventricular systolic pressure is related to the increase of C/T ratio (>0.55) in chest radiography (p<0.05) and increased brain natriuretic peptide in blood (p<0.05). Conclusion. The increase of C/T ratio (>0.55) in chest radiography was associated with increased right ventricular systolic pressure measured by echocardiography and inferred a role in early detection of asymptomatic pulmonary arterial hypertension in SSc patients. (J Rheum Dis 2015;22:19-24)

Keywords: Pulmonary hypertension, Systemic sclerosis

JRD
Jan 01, 2025 Vol.32 No.1, pp. 1~7
COVER PICTURE
Cumulative growth of rheumatology members and specialists (1980~2024). Cumulative distribution of the number of the (A) Korean College of Rheumatology members and (B) rheumatology specialists. (J Rheum Dis 2025;32:63-65)

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