Case Report
J Rheum Dis 2015; 22(3): 186-189
Published online June 30, 2015
© Korean College of Rheumatology
A Case of Varicelliform Zoster in a Patient Treated with Etanercept for Ankylosing Spondylitis
Correspondence to : Nak-Hyun Kim
Tumor necrosis factor-α (TNF-α) inhibitors are increasingly used in treatment of inflammatory disorders because of their im-munomodulatory efficacy. Increased risk of infection is an adverse effect of anti-TNF-α therapy. The incidence rate and severity of herpes zoster is significantly higher in patients on anti-TNF-α therapy than in the general population. The clinical pre-sentation of varicella zoster virus infection is also often atypical in these patients. We experienced a patient who presented with a disseminated varicelliform rash while on etanercept therapy for ankylosing spondylitis. (J Rheum Dis 2015;22:186-189)
Keywords Herpes zoster, TNFR-Fc fusion protein, Ankylosing spondylitis
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Case Report
J Rheum Dis 2015; 22(3): 186-189
Published online June 30, 2015
Copyright © Korean College of Rheumatology.
A Case of Varicelliform Zoster in a Patient Treated with Etanercept for Ankylosing Spondylitis
Sun Hee Na, Eun Young Nam, Pyoeng Gyun Choe, Wan Beom Park, Nam Joong Kim, Myoung-don Oh, Eun Young Lee, Nak-Hyun Kim
Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
Correspondence to:Nak-Hyun Kim
Abstract
Tumor necrosis factor-α (TNF-α) inhibitors are increasingly used in treatment of inflammatory disorders because of their im-munomodulatory efficacy. Increased risk of infection is an adverse effect of anti-TNF-α therapy. The incidence rate and severity of herpes zoster is significantly higher in patients on anti-TNF-α therapy than in the general population. The clinical pre-sentation of varicella zoster virus infection is also often atypical in these patients. We experienced a patient who presented with a disseminated varicelliform rash while on etanercept therapy for ankylosing spondylitis. (J Rheum Dis 2015;22:186-189)
Keywords: Herpes zoster, TNFR-Fc fusion protein, Ankylosing spondylitis
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