Case Report
J Rheum Dis 2017; 24(2): 119-122
Published online April 30, 2017
© Korean College of Rheumatology
Aseptic Meningitis and Acute Kidney Injury after Immunoglobulin Infusion in a Patient with Systemic Lupus Erythematosus and Immune Thrombocytopenic Purpura
Correspondence to : Yong-Gil Kim, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea. E-mail：bestmd2000@amc.seoul.kr
This is a Free Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.
A 36-yr-old woman with systemic lupus erythematosus was admitted in our center because of thrombocytopenia that was being treated with corticosteroids. She was prescribed a four-day course of intravenous immunoglobulin (IVIG) infusion. After three days of IVIG infusion, she developed aseptic meningitis with severe pleocytosis in the cerebrospinal fluid, followed by acute kidney injury. These complications resolved completely with conservative management. Here, we report these rare complications of IVIG and the outcome.
Keywords Systemic lupus erythematosus, Acute kidney injury, Aseptic meningitis, Intravenous immunoglobulin
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Case Report
J Rheum Dis 2017; 24(2): 119-122
Published online April 30, 2017 https://doi.org/10.4078/jrd.2017.24.2.119
Copyright © Korean College of Rheumatology.
Aseptic Meningitis and Acute Kidney Injury after Immunoglobulin Infusion in a Patient with Systemic Lupus Erythematosus and Immune Thrombocytopenic Purpura
Seokjung Jo, Eun Hye Oh, Jae Yong Lee, Yun Kyung Cho, Oh Chan Kwon, Byeongzu Ghang, Yong-Gil Kim
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Correspondence to:Yong-Gil Kim, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea. E-mail：bestmd2000@amc.seoul.kr
This is a Free Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
A 36-yr-old woman with systemic lupus erythematosus was admitted in our center because of thrombocytopenia that was being treated with corticosteroids. She was prescribed a four-day course of intravenous immunoglobulin (IVIG) infusion. After three days of IVIG infusion, she developed aseptic meningitis with severe pleocytosis in the cerebrospinal fluid, followed by acute kidney injury. These complications resolved completely with conservative management. Here, we report these rare complications of IVIG and the outcome.
Keywords: Systemic lupus erythematosus, Acute kidney injury, Aseptic meningitis, Intravenous immunoglobulin
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