Original
The Journal of the Korean Rheumatism Association 2003; 10(1): 39-44
Published online March 30, 2003
© Korean College of Rheumatology
류마티스 질환에서의 이차성 아밀로이드증
김태종·오승일·박준성·김태엽·박재홍·엄완식*·이혜순·전재범·정성수·배상철·유대현·김태환
한양대학교 의과대학 류마티스병원 류마티스내과, 순천향대학교 부천병원 류마티스내과*
Objective: To study the clinical features and outcomes in 10 cases of secondary amyloidosis with rheumatic disease.
Methods: The secondary amyloidosis associated with rheumatic disease was studied clinically in 10 patients (4 men and 6 women), who have suspicious tissue dysfunction. The diagnosis of amyloidosis was established by histological examination of biopsy materials. We evaluated them by medical record review; clinical features at onset, organ involvement, cause of death.
Results: The mean age and mean duration of rheumatic disease were 52.9⁑17.27 years and 10.9⁑10.33 years respectively. The common initial clinical features were generalized edema, diarrhea and abdominal pain. The mainly involved organs were kidney and colon. Causes of death were DIC due to sepsis and renal failure.
Conclusion: Renal and gastrointestinal symptoms are cardinal features of secondary amyloidosis with rheumatic disease in Korea.
Keywords Amyloidosis, Ankylosing spondylitis, Rheumatoid arthritis
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Original
The Journal of the Korean Rheumatism Association 2003; 10(1): 39-44
Published online March 30, 2003
Copyright © Korean College of Rheumatology.
류마티스 질환에서의 이차성 아밀로이드증
김태종·오승일·박준성·김태엽·박재홍·엄완식*·이혜순·전재범·정성수·배상철·유대현·김태환
한양대학교 의과대학 류마티스병원 류마티스내과, 순천향대학교 부천병원 류마티스내과*
The Secondary Amyloidosis in Rheumatic Diseases
Tae Jong Kim, M.D., Seung Il Oh, M.D., Joon Sung Park, M.D., Tae Yeob Kim, M.D., Jae-Hong Park, M.D., Wan-Sik Uhm, M.D.*, Hye-Soon Lee, M.D., Jae-Bum Jun, M.D., Sung-Soo Jung, M.D., Sang-Cheol Bae, M.D., Dae-Hyun Yoo, M.D., Tae-Hwan Kim, M.D.
The Hospital for Rheumatic Diseases, Hanyang University Medical Center, Seoul, Korea. Department of Internal Medicine, SoonChunHyang University Bucheon Hospital, Bucheon, Korea*
Correspondence to:Tae-Hwan Kim
Abstract
Objective: To study the clinical features and outcomes in 10 cases of secondary amyloidosis with rheumatic disease.
Methods: The secondary amyloidosis associated with rheumatic disease was studied clinically in 10 patients (4 men and 6 women), who have suspicious tissue dysfunction. The diagnosis of amyloidosis was established by histological examination of biopsy materials. We evaluated them by medical record review; clinical features at onset, organ involvement, cause of death.
Results: The mean age and mean duration of rheumatic disease were 52.9⁑17.27 years and 10.9⁑10.33 years respectively. The common initial clinical features were generalized edema, diarrhea and abdominal pain. The mainly involved organs were kidney and colon. Causes of death were DIC due to sepsis and renal failure.
Conclusion: Renal and gastrointestinal symptoms are cardinal features of secondary amyloidosis with rheumatic disease in Korea.
Keywords: Amyloidosis, Ankylosing spondylitis, Rheumatoid arthritis
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