Original

The Journal of the Korean Rheumatism Association 2004; 11(2): 174-178

Published online June 30, 2004

© Korean College of Rheumatology

신증후군을 동반한 전신성 홍반성 루푸스-전신성 경화증 중복 증후군 1예

윤보영·이찬희·한성훈·이윤우

인제대학교 의과대학 내과학교실

A Case of SLE-systemic Sclerosis Overlap Syndrome Complicated with Nephrotic Syndrome

Bo Young Yoon, M.D., Chan Hee Lee, M.D., Ph.D., Seong Hoon Han, M.D., Yun Woo Lee, M.D., Ph.D.

Department of Internal Medicine, College of Medicine, Inje University

Correspondence to : Bo Young Yoon

Abstract

Renal manifestations of systemic sclerosis are proteinuria, hypertension, azotemia and renal crisis. Mild proteinuria is common, but the nephrotic syndrome occurring in association with systemic sclerosis has been rarely reported. The majority of nephrotic syndrome cases are caused by glomerulonephritis in patients with an overlap syndrome of SLE and systemic sclerosis. This report suggests that the nephrotic syndrome can be an infrequent sequel of systemic sclerosis alone without glomerulopathy. A 38-year old woman was suffering from visual loss and headaches. She had Raynaud's phenomenon and thickened skin on nearly whole body. Urine protein was 4,950 mg/day and serum albumin level was 2.7 g/dL. The result of renal biopsy was renovasculopathy-compatible with systemic sclerosis.

Keywords Systemic sclerosis, Nephrotic syndrome, Overlap syndrome

Article

Original

The Journal of the Korean Rheumatism Association 2004; 11(2): 174-178

Published online June 30, 2004

Copyright © Korean College of Rheumatology.

신증후군을 동반한 전신성 홍반성 루푸스-전신성 경화증 중복 증후군 1예

윤보영·이찬희·한성훈·이윤우

인제대학교 의과대학 내과학교실

A Case of SLE-systemic Sclerosis Overlap Syndrome Complicated with Nephrotic Syndrome

Bo Young Yoon, M.D., Chan Hee Lee, M.D., Ph.D., Seong Hoon Han, M.D., Yun Woo Lee, M.D., Ph.D.

Department of Internal Medicine, College of Medicine, Inje University

Correspondence to:Bo Young Yoon

Abstract

Renal manifestations of systemic sclerosis are proteinuria, hypertension, azotemia and renal crisis. Mild proteinuria is common, but the nephrotic syndrome occurring in association with systemic sclerosis has been rarely reported. The majority of nephrotic syndrome cases are caused by glomerulonephritis in patients with an overlap syndrome of SLE and systemic sclerosis. This report suggests that the nephrotic syndrome can be an infrequent sequel of systemic sclerosis alone without glomerulopathy. A 38-year old woman was suffering from visual loss and headaches. She had Raynaud's phenomenon and thickened skin on nearly whole body. Urine protein was 4,950 mg/day and serum albumin level was 2.7 g/dL. The result of renal biopsy was renovasculopathy-compatible with systemic sclerosis.

Keywords: Systemic sclerosis, Nephrotic syndrome, Overlap syndrome

JRD
Jan 01, 2025 Vol.32 No.1, pp. 1~7
COVER PICTURE
Cumulative growth of rheumatology members and specialists (1980~2024). Cumulative distribution of the number of the (A) Korean College of Rheumatology members and (B) rheumatology specialists. (J Rheum Dis 2025;32:63-65)

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