Original Article

The Journal of the Korean Rheumatism Association 2004; 11(3): 227-234

Published online September 30, 2004

© Korean College of Rheumatology

류마티스관절염 환자의 임상적 특징과 관절침범 양상

윤보영·이찬희·한성훈·이윤우

인제대학교 의과대학 내과학교실

Clinical Characteristics and Joint Involvement of Rheumatoid Arthritis

Bo Young Yoon, M.D., Chan Hee Lee, M.D., Ph.D., Seong Hoon Han, M.D., Yun Woo Lee, M.D., Ph.D.

Department of Internal Medicine, College of Medicine, Inje University

Correspondence to : Bo Young Yoon

Abstract

Objective: To investigate the clinical, laboratory, radiologic characteristics, and joint involvement of rheumatoid arthritis (RA) in Korean. Methods: We retrospectively reviewed initial medical records of 210 patients diagnosed as rheumatoid arthritis in Seoul, Sanggye, and Ilsan Paik Hospital, Inje University. Evaluation included age, sex, disease duration, duration of morning stiffness, joint involvement, the number of tender and swollen joints, rheumatoid factor, erythrocyte sedimentation rate (ESR), C- reactive protein (CRP), and bony erosion in simple X-ray. Results: In total 210 patients, mean age was 50.1±13.5 years, and male to female ratio was 1 to 5.6. Mean duration of arthritis was 51.8±72.6 months and positive rate of rheumatoid factor was 66.7%. Mean time interval between symptom onset and first visit was 14.1±19.1 months. Bony erosion rate was 15.3% in early RA patients, who had been diagnosed as RA within 1 year. The order of frequency of joint involvement was as the follows; metacarpophalangeal (MCP) joints, wrist joints, proximal interphalangeal (PIP) joints, metatarsophalangeal (MTP) joints, ankle joints, and knee joints. It was noted that the joints on the right and left sides behaved in like fashion. This pattern was not different with early RA. The titer of rheumatoid factor showed poor correlations with variables of clinical activity (ESR, CRP, duration of morning stiffness, and number of tender and swollen joints).Conclusion: In Korea, clinical manifestations and joint involvement of RA patients were not different from other published studies. The most commonly involved joints are MCP joints, wrist joints, PIP joints, and MTP joints.

Keywords Rheumatoid arthritis, Clinical characteristics, Joint involvement

Article

Original Article

The Journal of the Korean Rheumatism Association 2004; 11(3): 227-234

Published online September 30, 2004

Copyright © Korean College of Rheumatology.

류마티스관절염 환자의 임상적 특징과 관절침범 양상

윤보영·이찬희·한성훈·이윤우

인제대학교 의과대학 내과학교실

Clinical Characteristics and Joint Involvement of Rheumatoid Arthritis

Bo Young Yoon, M.D., Chan Hee Lee, M.D., Ph.D., Seong Hoon Han, M.D., Yun Woo Lee, M.D., Ph.D.

Department of Internal Medicine, College of Medicine, Inje University

Correspondence to:Bo Young Yoon

Abstract

Objective: To investigate the clinical, laboratory, radiologic characteristics, and joint involvement of rheumatoid arthritis (RA) in Korean. Methods: We retrospectively reviewed initial medical records of 210 patients diagnosed as rheumatoid arthritis in Seoul, Sanggye, and Ilsan Paik Hospital, Inje University. Evaluation included age, sex, disease duration, duration of morning stiffness, joint involvement, the number of tender and swollen joints, rheumatoid factor, erythrocyte sedimentation rate (ESR), C- reactive protein (CRP), and bony erosion in simple X-ray. Results: In total 210 patients, mean age was 50.1±13.5 years, and male to female ratio was 1 to 5.6. Mean duration of arthritis was 51.8±72.6 months and positive rate of rheumatoid factor was 66.7%. Mean time interval between symptom onset and first visit was 14.1±19.1 months. Bony erosion rate was 15.3% in early RA patients, who had been diagnosed as RA within 1 year. The order of frequency of joint involvement was as the follows; metacarpophalangeal (MCP) joints, wrist joints, proximal interphalangeal (PIP) joints, metatarsophalangeal (MTP) joints, ankle joints, and knee joints. It was noted that the joints on the right and left sides behaved in like fashion. This pattern was not different with early RA. The titer of rheumatoid factor showed poor correlations with variables of clinical activity (ESR, CRP, duration of morning stiffness, and number of tender and swollen joints).Conclusion: In Korea, clinical manifestations and joint involvement of RA patients were not different from other published studies. The most commonly involved joints are MCP joints, wrist joints, PIP joints, and MTP joints.

Keywords: Rheumatoid arthritis, Clinical characteristics, Joint involvement

JRD
Oct 01, 2024 Vol.31 No.4, pp. 191~263
COVER PICTURE
Ancestry-driven pathways for SLE-risk SNP-associated genes. The ancestry-driven key signaling pathways in Asians, Europeans, and African Americans were analyzed by enrichr (https://maayanlab.cloud/Enrichr/#libraries) using non-HLA SNP-associated genes. SLE: systemic lupus erythematosus, SNP: single-nucleotide polymorphism, JAK–STAT: janus kinase–signal transducers and activators of transcription, IFN: interferon gamma. (J Rheum Dis 2024;31:200-211)

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