Case Report
The Journal of the Korean Rheumatism Association 2005; 12(1): 47-51
Published online March 30, 2005
© Korean College of Rheumatology
루푸스 신염 환자에서 발생한 폐 Nocardia 감염증 1예
장선주*·이강녕*·성윤경·이혜순·엄완식·김태환·전재범·배현주*·배상철·전석철**·유대현
한양대학교 의과대학 내과학교실*, 류마티스병원, 진단방사선과학교실**
Pulmonary Nocardiosis in a Patient with Lupus Nephritis
Correspondence to : Dae-Hyun Yoo
Nocardiosis is uncommon in healthy people, but occurs as an opportunistic infection in patients with connective tissue disease, solid organ transplantation, lung disease, malignancies, and the acquired immune deficiency syndrome (AIDS). Nocardia is a gram positive, variably acid-fast aerobic bacterium of the family Nocardiaceae characterized by branching and filamentous growth, with distinctive aerial hyphae. In systemic lupus erythematosus (SLE) patients, immunosuppressiion with cytotoxic drugs or corticosteroids, proteinuria, renal insufficiency, and active SLE itself are known as risk factors for serious bacterial infections and opportunistic infections. We report a case of pulmonary Nocardiosis in patient with lupus nephritis treated with cyclophosphamide and high dose corticosteroid.
Keywords Systemic lupus erythematosus, Lupus nephritis, Nocardia, Pulmonary Nocardiosis, Acquired immune deficiency syndrome
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Case Report
The Journal of the Korean Rheumatism Association 2005; 12(1): 47-51
Published online March 30, 2005
Copyright © Korean College of Rheumatology.
루푸스 신염 환자에서 발생한 폐 Nocardia 감염증 1예
장선주*·이강녕*·성윤경·이혜순·엄완식·김태환·전재범·배현주*·배상철·전석철**·유대현
한양대학교 의과대학 내과학교실*, 류마티스병원, 진단방사선과학교실**
Pulmonary Nocardiosis in a Patient with Lupus Nephritis
Sun-Joo Chang, M.D.*, Kang-Nyoung Lee, M.D.*, Yoon-Kyoung Sung, M.D., Hye-Soon Lee, M.D., Wan-Sik Uhm, M.D., Tae-Hwan Kim, M.D., Jae-Bum Jun, M.D., Hyun-Joo Pai, M.D.*, Sang-Cheol Bae, M.D., Seok-Chol Jeon, M.D.**, Dae-Hyun Yoo, M.D.
Division of Rheumatology, The Hospital for Rheumatic Diseases, Department of Internal Medicine*, Department of Radiology**, Hanyang University College of Medicine, Seoul, Korea
Correspondence to:Dae-Hyun Yoo
Abstract
Nocardiosis is uncommon in healthy people, but occurs as an opportunistic infection in patients with connective tissue disease, solid organ transplantation, lung disease, malignancies, and the acquired immune deficiency syndrome (AIDS). Nocardia is a gram positive, variably acid-fast aerobic bacterium of the family Nocardiaceae characterized by branching and filamentous growth, with distinctive aerial hyphae. In systemic lupus erythematosus (SLE) patients, immunosuppressiion with cytotoxic drugs or corticosteroids, proteinuria, renal insufficiency, and active SLE itself are known as risk factors for serious bacterial infections and opportunistic infections. We report a case of pulmonary Nocardiosis in patient with lupus nephritis treated with cyclophosphamide and high dose corticosteroid.
Keywords: Systemic lupus erythematosus, Lupus nephritis, Nocardia, Pulmonary Nocardiosis, Acquired immune deficiency syndrome
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