The Journal of the Korean Rheumatism Association 2006; 13(4): 348-352
Published online December 30, 2006
© Korean College of Rheumatology
박태진·최길순·박한정·조대열·정재욱·박해심·정재연*·김영배**·심철**·서창희
아주대학교 의과대학 알레르기-류마티스내과학교실, 소화기내과학교실*, 병리학교실**
Correspondence to : Chang-Hee Suh
The coexistence of polymyositis and primary biliary cirrhosis is rare. Both are characterized by chronic inflammation and immunological abnormalities. We report a case of 54-year-old female patient presenting with these two autoimmune diseases. She exhibited symmetrical proximal muscle weakness and elevated serum levels of muscle enzymes. Polymyositis was confirmed by electromyography and muscle biopsy. The diagnosis of primary biliary cirrhosis was based on increased serum levels of alkaline phosphatase, IgM immunoglobulin, presence of antimitochodrial antibody and characteristic liver biopy findings. This is the first case who manifest polymyositis and primary biliary cirrhosis simultaneously in Korea.
Keywords Polymyositis, Primary biliary cirrhosis
The Journal of the Korean Rheumatism Association 2006; 13(4): 348-352
Published online December 30, 2006
Copyright © Korean College of Rheumatology.
박태진·최길순·박한정·조대열·정재욱·박해심·정재연*·김영배**·심철**·서창희
아주대학교 의과대학 알레르기-류마티스내과학교실, 소화기내과학교실*, 병리학교실**
Tae-Jin Park, M.D., Gil-Soon Choi, M.D., Han-Jung Park, M.D., Dai-Yeol Joe, M.D., Jae-Wook Chung, M.D., Hae-Sim Park, M.D., Jae-Youn Cheong, M.D.*, Young-Bae Kim, M.D.**, Chull Shim, M.D.**, Chang-Hee Suh, M.D.
Departments of Allergy & Rheumatology, Gastroenterology*, and Pathology**, Ajou University School of Medicine, Suwon, Korea
Correspondence to:Chang-Hee Suh
The coexistence of polymyositis and primary biliary cirrhosis is rare. Both are characterized by chronic inflammation and immunological abnormalities. We report a case of 54-year-old female patient presenting with these two autoimmune diseases. She exhibited symmetrical proximal muscle weakness and elevated serum levels of muscle enzymes. Polymyositis was confirmed by electromyography and muscle biopsy. The diagnosis of primary biliary cirrhosis was based on increased serum levels of alkaline phosphatase, IgM immunoglobulin, presence of antimitochodrial antibody and characteristic liver biopy findings. This is the first case who manifest polymyositis and primary biliary cirrhosis simultaneously in Korea.
Keywords: Polymyositis, Primary biliary cirrhosis
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