Case Report

The Journal of the Korean Rheumatism Association 2007; 14(4): 379-383

Published online December 30, 2007

© Korean College of Rheumatology

전신성 경화증에 동반된 소장의 거짓폐쇄를 Octreotide와 Erythromycin 병합요법으로 치료한 1예

윤현성ㆍ서태호ㆍ조한수ㆍ이응준ㆍ김범성ㆍ김해림ㆍ이상헌

건국대학교 의과대학 내과학교실 류마티스내과

A Case of Intestinal Pseudoobstruction Associated with Systemic Sclerosis Successfully Treated with Erythromycin and Octreotide

Hyun Sung Yoon, M.D., Tae Ho Seo, M.D., Han Soo Jo, M.D., Eung Jun Lee, M.D., Byum Sung Kim, M.D., Hae-Rim Kim, M.D., Sang-Heon Lee, M.D.

Division of Rheumatology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea

Correspondence to : Sang-Heon Lee

Abstract

Systemic sclerosis is an autoimmune disease, characterized by inflammation, microangiopathy and fibrosis in the skin and various intestinal organs. Gastrointestinal involvement is one of the major causes of serious morbidity, and next to the skin, the gastrointestinal tract is the most commonly involved organ. While esophageal involvement is most common gastrointestinal manifestation, the involvement of the small intestine and colon is less common but may lead to life-threatening complications like chronic pesudoobstruction or pneumatosis cystoids intestinalis. Here, we describe a case of progressive systemic sclerosis associated with intestinal pseudoobstruction. 28 year-old male presented abdominal pain and vomiting and he was diagnosed as having intestinal pseudoobstruction. His symptoms were well managed using the combination of octreotide, a long-acting somatostatin analogue, and erythromycin.

Keywords Systemic sclerosis, Intestinal pseudoobstruction, Octreotide, Erythromycin

Article

Case Report

The Journal of the Korean Rheumatism Association 2007; 14(4): 379-383

Published online December 30, 2007

Copyright © Korean College of Rheumatology.

전신성 경화증에 동반된 소장의 거짓폐쇄를 Octreotide와 Erythromycin 병합요법으로 치료한 1예

윤현성ㆍ서태호ㆍ조한수ㆍ이응준ㆍ김범성ㆍ김해림ㆍ이상헌

건국대학교 의과대학 내과학교실 류마티스내과

A Case of Intestinal Pseudoobstruction Associated with Systemic Sclerosis Successfully Treated with Erythromycin and Octreotide

Hyun Sung Yoon, M.D., Tae Ho Seo, M.D., Han Soo Jo, M.D., Eung Jun Lee, M.D., Byum Sung Kim, M.D., Hae-Rim Kim, M.D., Sang-Heon Lee, M.D.

Division of Rheumatology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea

Correspondence to:Sang-Heon Lee

Abstract

Systemic sclerosis is an autoimmune disease, characterized by inflammation, microangiopathy and fibrosis in the skin and various intestinal organs. Gastrointestinal involvement is one of the major causes of serious morbidity, and next to the skin, the gastrointestinal tract is the most commonly involved organ. While esophageal involvement is most common gastrointestinal manifestation, the involvement of the small intestine and colon is less common but may lead to life-threatening complications like chronic pesudoobstruction or pneumatosis cystoids intestinalis. Here, we describe a case of progressive systemic sclerosis associated with intestinal pseudoobstruction. 28 year-old male presented abdominal pain and vomiting and he was diagnosed as having intestinal pseudoobstruction. His symptoms were well managed using the combination of octreotide, a long-acting somatostatin analogue, and erythromycin.

Keywords: Systemic sclerosis, Intestinal pseudoobstruction, Octreotide, Erythromycin

JRD
Jan 01, 2025 Vol.32 No.1, pp. 1~7
COVER PICTURE
Cumulative growth of rheumatology members and specialists (1980~2024). Cumulative distribution of the number of the (A) Korean College of Rheumatology members and (B) rheumatology specialists. (J Rheum Dis 2025;32:63-65)

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