Case Report

The Journal of the Korean Rheumatism Association 2007; 14(4): 401-406

Published online December 30, 2007

© Korean College of Rheumatology

피부근염 환자에서 빠르게 진행한 간질성폐렴 1예

윤재영ㆍ민선양ㆍ박주이ㆍ홍승권ㆍ강효종

분당제생병원 내과

Rapidly Progressive Interstitial Lung Disease Associated with Dermatomyositis; A Case Report

Jae Young Yoon, M.D., Sun Yang Min, M.D., Ju Yee Park, M.D., Seung Goun Hong, M.D., Hyo Jong Kang, M.D.

Department of Internal Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea

Correspondence to : Hyo Jong Kang

Abstract

A previously healthy 44-year-old woman who was diagnosed as having dermatomyositis suddenly developed severe dyspnea while being in the state of improved condition of muscle weakness. Interstitial lung disease was found on high resolution computed tomography (HRCT). In spite of the treatment with the immune-modulating agent (high dose steroid, cyclophosphamide, immunoglubulin and cyclosporine), her condition deteriorated further and rapidly, leading to death. More intensive agent such as FK506 would be necessary in those cases of dermatomyositis-related interstitial lung disease that have poor prognostic factors.

Keywords Interstitial lung disease, Dermatomyositis

Article

Case Report

The Journal of the Korean Rheumatism Association 2007; 14(4): 401-406

Published online December 30, 2007

Copyright © Korean College of Rheumatology.

피부근염 환자에서 빠르게 진행한 간질성폐렴 1예

윤재영ㆍ민선양ㆍ박주이ㆍ홍승권ㆍ강효종

분당제생병원 내과

Rapidly Progressive Interstitial Lung Disease Associated with Dermatomyositis; A Case Report

Jae Young Yoon, M.D., Sun Yang Min, M.D., Ju Yee Park, M.D., Seung Goun Hong, M.D., Hyo Jong Kang, M.D.

Department of Internal Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea

Correspondence to:Hyo Jong Kang

Abstract

A previously healthy 44-year-old woman who was diagnosed as having dermatomyositis suddenly developed severe dyspnea while being in the state of improved condition of muscle weakness. Interstitial lung disease was found on high resolution computed tomography (HRCT). In spite of the treatment with the immune-modulating agent (high dose steroid, cyclophosphamide, immunoglubulin and cyclosporine), her condition deteriorated further and rapidly, leading to death. More intensive agent such as FK506 would be necessary in those cases of dermatomyositis-related interstitial lung disease that have poor prognostic factors.

Keywords: Interstitial lung disease, Dermatomyositis

JRD
Oct 01, 2024 Vol.31 No.4, pp. 191~263
COVER PICTURE
Ancestry-driven pathways for SLE-risk SNP-associated genes. The ancestry-driven key signaling pathways in Asians, Europeans, and African Americans were analyzed by enrichr (https://maayanlab.cloud/Enrichr/#libraries) using non-HLA SNP-associated genes. SLE: systemic lupus erythematosus, SNP: single-nucleotide polymorphism, JAK–STAT: janus kinase–signal transducers and activators of transcription, IFN: interferon gamma. (J Rheum Dis 2024;31:200-211)

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