The Journal of the Korean Rheumatism Association 2009; 16(3): 181-188
Published online September 30, 2009
© Korean College of Rheumatology
조미라1ㆍ박영은1ㆍ백승훈1ㆍ이정욱2ㆍ김근태3ㆍ이준희4ㆍ추기석5ㆍ정연주5ㆍ이선희1ㆍ김성일1
부산대학교 의과대학 내과학교실1, 부산성모병원 내과2, 고신대학교 의과대학 내과학교실3, 춘해병원 내과4, 부산대학교 의과대학 영상의학교실5
Correspondence to : Sung Il Kim
Objective: There is some controversy regarding the early onset or high incidence of coronary atherosclerosis in patients with systemic sclerosis (SSc). Measurements of the coronary calcification score (CCS) by multi-detector computed tomography (MDCT) is an accurate and non-invasive method for detecting coronary atherosclerosis, and a high level of CCS (≥160) can predict coronary events. This study examined the CCS using MDCT and evaluated the risk of coronary events in patients with SSc.
Methods: The clinical and laboratory characteristics of 35 patients with SSc were examined. The CCS was measured by MDCT, and the risk of coronary events were evaluated by CCS and the Framingham risk score (FRS).
Results: In 35 patients (2 males and 33 females, 20 with limited and 15 with diffuse type), the mean age was 52±12 years and the disease duration was 8±7 years. The mean CCS was 10.1±30.8, the CCS of 28 patients (80%) was 0, and all patients had a CCS<160. The CCS had no significant correlation with the clinical and laboratory characteristics. The FRS was evaluated in 29 patients. Twenty eight patients were categorized into the low-risk group (FRS<10%) and only one was classified into the moderate-risk group (FRS=13%).
Conclusion: These results suggest that the risk of coronary events due to coronary atherosclerosis might not be high in patients with SSc.
Keywords Systemic sclerosis, Coronary arteries, Pathologic calcification
The Journal of the Korean Rheumatism Association 2009; 16(3): 181-188
Published online September 30, 2009
Copyright © Korean College of Rheumatology.
조미라1ㆍ박영은1ㆍ백승훈1ㆍ이정욱2ㆍ김근태3ㆍ이준희4ㆍ추기석5ㆍ정연주5ㆍ이선희1ㆍ김성일1
부산대학교 의과대학 내과학교실1, 부산성모병원 내과2, 고신대학교 의과대학 내과학교실3, 춘해병원 내과4, 부산대학교 의과대학 영상의학교실5
Mi Ra Cho1, Young Eun Park1, Seung Hoon Baek1, Joung Wook Lee2, Geun Tae Kim3, Jun Hee Lee4, Ki Seok Choo5, Yeon-Ju Jeong5, Sun Hee Lee1, Sung Il Kim1
Department of Internal Medicine, School of Medicine, Pusan National University1, Busan St. Mary's Medical Center2, Kosin University3, Choonhae Hospital4, Department of Radiology, School of Medicine, Pusan National University5, Busan, Korea
Correspondence to:Sung Il Kim
Objective: There is some controversy regarding the early onset or high incidence of coronary atherosclerosis in patients with systemic sclerosis (SSc). Measurements of the coronary calcification score (CCS) by multi-detector computed tomography (MDCT) is an accurate and non-invasive method for detecting coronary atherosclerosis, and a high level of CCS (≥160) can predict coronary events. This study examined the CCS using MDCT and evaluated the risk of coronary events in patients with SSc.
Methods: The clinical and laboratory characteristics of 35 patients with SSc were examined. The CCS was measured by MDCT, and the risk of coronary events were evaluated by CCS and the Framingham risk score (FRS).
Results: In 35 patients (2 males and 33 females, 20 with limited and 15 with diffuse type), the mean age was 52±12 years and the disease duration was 8±7 years. The mean CCS was 10.1±30.8, the CCS of 28 patients (80%) was 0, and all patients had a CCS<160. The CCS had no significant correlation with the clinical and laboratory characteristics. The FRS was evaluated in 29 patients. Twenty eight patients were categorized into the low-risk group (FRS<10%) and only one was classified into the moderate-risk group (FRS=13%).
Conclusion: These results suggest that the risk of coronary events due to coronary atherosclerosis might not be high in patients with SSc.
Keywords: Systemic sclerosis, Coronary arteries, Pathologic calcification
Bong-Woo Lee, M.D., Eui-Jong Kwon, M.D., Ji Hyeon Ju, M.D., Ph.D.
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