Case Report

The Journal of the Korean Rheumatism Association 2010; 17(1): 93-97

Published online March 30, 2010

© Korean College of Rheumatology

류마티스관절염 환자에서 익상편수술 후 발생한 천공성 공막연화증 1예

김재희1ㆍ김현옥1ㆍ정용근1ㆍ윤성은1ㆍ이경주1ㆍ이창민1ㆍ김완수1ㆍ송준경2,3ㆍ이상일1,3

경상대학교 의학전문대학원 내과학교실1, 안과학교실2, 건강과학연구원3

A Case of Scleromalacia Perforance That Developing after Surgery for Excision of the Pterygium in a Patient with Rheumatoid Arthritis

Jae Hee Kim1, Hyun Ok Kim1, Yong Geun Jeong1, Seong Un Yun1, Kyeong Ju Lee1, Chang Min Lee1, Wan Soo Kim1, Joon Kyung Song2,3, Sang-Il Lee1,3

Departments of Internal Medicine1, and Ophthalmology2, Institute of Health Sciences3, Gyeongsang National University School of Medicine, Jinju, Korea

Correspondence to : Sang-Il Lee

Abstract

The ocular manifestations of rheumatoid arthritis (RA) are common and they can vary from patient to patient. However, necrotizing anterior scleritis without inflammation (scleromalacia perforans) is a rare and serious opthalmic complication, and it is typically associated with long-standing RA. Although the etiology and pathogenesis of scleromalacia perforans are diverse and they are not completely understood, ophthalmic surgery is one of the well known causes of scleromalacia perforans. Patients with systemic autoimmune disease such as RA have an especially higher risk of scleromalacia perforans after opthalmic surgery. Because scleromalacia perforans is a potential threat not just to eyesight, but to life as well, early diagnosis and prompt treatment are required for its successful management. We experienced a case of scleromalacia perforans that developed after scleral excision of pterygium in a 58 year old woman who had a 7 year history of RA, and this was well treated with an early screral graft. We report here on this case along with a review of the relevant literature.

Keywords Rheumatoid arthritis, Scleromalacia perforans, Pterygium

Article

Case Report

The Journal of the Korean Rheumatism Association 2010; 17(1): 93-97

Published online March 30, 2010

Copyright © Korean College of Rheumatology.

류마티스관절염 환자에서 익상편수술 후 발생한 천공성 공막연화증 1예

김재희1ㆍ김현옥1ㆍ정용근1ㆍ윤성은1ㆍ이경주1ㆍ이창민1ㆍ김완수1ㆍ송준경2,3ㆍ이상일1,3

경상대학교 의학전문대학원 내과학교실1, 안과학교실2, 건강과학연구원3

A Case of Scleromalacia Perforance That Developing after Surgery for Excision of the Pterygium in a Patient with Rheumatoid Arthritis

Jae Hee Kim1, Hyun Ok Kim1, Yong Geun Jeong1, Seong Un Yun1, Kyeong Ju Lee1, Chang Min Lee1, Wan Soo Kim1, Joon Kyung Song2,3, Sang-Il Lee1,3

Departments of Internal Medicine1, and Ophthalmology2, Institute of Health Sciences3, Gyeongsang National University School of Medicine, Jinju, Korea

Correspondence to:Sang-Il Lee

Abstract

The ocular manifestations of rheumatoid arthritis (RA) are common and they can vary from patient to patient. However, necrotizing anterior scleritis without inflammation (scleromalacia perforans) is a rare and serious opthalmic complication, and it is typically associated with long-standing RA. Although the etiology and pathogenesis of scleromalacia perforans are diverse and they are not completely understood, ophthalmic surgery is one of the well known causes of scleromalacia perforans. Patients with systemic autoimmune disease such as RA have an especially higher risk of scleromalacia perforans after opthalmic surgery. Because scleromalacia perforans is a potential threat not just to eyesight, but to life as well, early diagnosis and prompt treatment are required for its successful management. We experienced a case of scleromalacia perforans that developed after scleral excision of pterygium in a 58 year old woman who had a 7 year history of RA, and this was well treated with an early screral graft. We report here on this case along with a review of the relevant literature.

Keywords: Rheumatoid arthritis, Scleromalacia perforans, Pterygium

JRD
Oct 01, 2024 Vol.31 No.4, pp. 191~263
COVER PICTURE
Ancestry-driven pathways for SLE-risk SNP-associated genes. The ancestry-driven key signaling pathways in Asians, Europeans, and African Americans were analyzed by enrichr (https://maayanlab.cloud/Enrichr/#libraries) using non-HLA SNP-associated genes. SLE: systemic lupus erythematosus, SNP: single-nucleotide polymorphism, JAK–STAT: janus kinase–signal transducers and activators of transcription, IFN: interferon gamma. (J Rheum Dis 2024;31:200-211)

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