Case Report

The Journal of the Korean Rheumatism Association 2010; 17(2): 194-199

Published online June 30, 2010

© Korean College of Rheumatology

전신홍반루푸스 환자에 동반된 파종성 효모균증 1예

정혜련1ㆍ권현희1ㆍ최정윤1,2

대구가톨릭대학교 의과대학 내과학교실1, 대구가톨릭대학교 관절염연구소2

A Case of Disseminated Crytococcosis in a Patient with Systemic Lupus Erythematosus

Hye Ryun Jung1, Hyun Hee Kwon1, Jung-Yoon Choe1,2

Department of Internal Medicine, School of Medicine1, Arthritis and Autoimmunity Research Center2, Catholic University of Daegu, Daegu, Korea

Correspondence to : Hyun Hee Kwon

Abstract

Disseminated cryptococcosis mainly occurs in immunocompromised patients. It enters the body through the respiratory tract and spreads to the lungs, skin, liver and lymphoid organs. Among cryptococcosis, cryptococcal meningitis is a relatively frequent manifestation and causes serious morbidity and mortality. It needs urgent diagnosis and initiation of effective antifungal therapy. It is difficult to differentiate cryptococcal meningitis from neuropsychiatric lupus due to similar clinical symptoms, laboratory and cerebrospinal fluid findings. We report a case of disseminated cyrptococcosis in a patient with systemic lupus erythematosus being managed with mycophenolate mofetil, prednisolone and hydroxychloroquine.

Keywords Disseminated cryptococcosis, Systemic lupus erythematosus

Article

Case Report

The Journal of the Korean Rheumatism Association 2010; 17(2): 194-199

Published online June 30, 2010

Copyright © Korean College of Rheumatology.

전신홍반루푸스 환자에 동반된 파종성 효모균증 1예

정혜련1ㆍ권현희1ㆍ최정윤1,2

대구가톨릭대학교 의과대학 내과학교실1, 대구가톨릭대학교 관절염연구소2

A Case of Disseminated Crytococcosis in a Patient with Systemic Lupus Erythematosus

Hye Ryun Jung1, Hyun Hee Kwon1, Jung-Yoon Choe1,2

Department of Internal Medicine, School of Medicine1, Arthritis and Autoimmunity Research Center2, Catholic University of Daegu, Daegu, Korea

Correspondence to:Hyun Hee Kwon

Abstract

Disseminated cryptococcosis mainly occurs in immunocompromised patients. It enters the body through the respiratory tract and spreads to the lungs, skin, liver and lymphoid organs. Among cryptococcosis, cryptococcal meningitis is a relatively frequent manifestation and causes serious morbidity and mortality. It needs urgent diagnosis and initiation of effective antifungal therapy. It is difficult to differentiate cryptococcal meningitis from neuropsychiatric lupus due to similar clinical symptoms, laboratory and cerebrospinal fluid findings. We report a case of disseminated cyrptococcosis in a patient with systemic lupus erythematosus being managed with mycophenolate mofetil, prednisolone and hydroxychloroquine.

Keywords: Disseminated cryptococcosis, Systemic lupus erythematosus

JRD
Jan 01, 2025 Vol.32 No.1, pp. 1~7
COVER PICTURE
Cumulative growth of rheumatology members and specialists (1980~2024). Cumulative distribution of the number of the (A) Korean College of Rheumatology members and (B) rheumatology specialists. (J Rheum Dis 2025;32:63-65)

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