Review Article

The Journal of the Korean Rheumatism Association 2010; 17(4): 340-347

Published online December 30, 2010

© Korean College of Rheumatology

강직성척추염의 자기공명영상 소견

이소연1ㆍ지원희2

가톨릭대학교 여의도성모병원 영상의학과1, 가톨릭대학교 서울성모병원 영상의학과2

MR Imaging of Ankylosing Spondylitis

So-Yeon Lee1, Won-Hee Jee2

Department of Radiology, Yeouido St. Mary's Hospital1, Seoul St. Mary's Hospital2, The Catholic University of Korea, Seoul, Korea

Correspondence to : Won-Hee Jee

Abstract

Magnetic resonance imaging (MRI) is a highly reliable tool for diagnosing ankylosing spondylitis. MRI can identify cartilage abnormalities, subcortical erosions, bone marrow edema with inflammation, and synovial enhancement. Subchondral sclerosis and juxta-articular fat deposition are noted in the chronic stage of ankylosing spondylitis. Spinal changes associated with spondyloarthropathy are florid anterior spondylitis (or Romanus lesion), florid diskitis (Anderson lesion), ankylosis, and arthritis of the apophyseal and costovertebral joints. A MRI grading system for inflammation in sacroiliac joints and the spine could help clinicians evaluate the anti-inflammatory efficacy of therapeutics. Newer technologies based on MRI are aimed at broadening the diagnostic scope and facilitating the quantification of active inflammation but still require extensive validation.

Keywords Ankylosing spondylitis, Spondyloarthropathies, Sacroiliitis, Magnetic resonance imaging

Article

Review Article

The Journal of the Korean Rheumatism Association 2010; 17(4): 340-347

Published online December 30, 2010

Copyright © Korean College of Rheumatology.

강직성척추염의 자기공명영상 소견

이소연1ㆍ지원희2

가톨릭대학교 여의도성모병원 영상의학과1, 가톨릭대학교 서울성모병원 영상의학과2

MR Imaging of Ankylosing Spondylitis

So-Yeon Lee1, Won-Hee Jee2

Department of Radiology, Yeouido St. Mary's Hospital1, Seoul St. Mary's Hospital2, The Catholic University of Korea, Seoul, Korea

Correspondence to:Won-Hee Jee

Abstract

Magnetic resonance imaging (MRI) is a highly reliable tool for diagnosing ankylosing spondylitis. MRI can identify cartilage abnormalities, subcortical erosions, bone marrow edema with inflammation, and synovial enhancement. Subchondral sclerosis and juxta-articular fat deposition are noted in the chronic stage of ankylosing spondylitis. Spinal changes associated with spondyloarthropathy are florid anterior spondylitis (or Romanus lesion), florid diskitis (Anderson lesion), ankylosis, and arthritis of the apophyseal and costovertebral joints. A MRI grading system for inflammation in sacroiliac joints and the spine could help clinicians evaluate the anti-inflammatory efficacy of therapeutics. Newer technologies based on MRI are aimed at broadening the diagnostic scope and facilitating the quantification of active inflammation but still require extensive validation.

Keywords: Ankylosing spondylitis, Spondyloarthropathies, Sacroiliitis, Magnetic resonance imaging

JRD
Oct 01, 2024 Vol.31 No.4, pp. 191~263
COVER PICTURE
Ancestry-driven pathways for SLE-risk SNP-associated genes. The ancestry-driven key signaling pathways in Asians, Europeans, and African Americans were analyzed by enrichr (https://maayanlab.cloud/Enrichr/#libraries) using non-HLA SNP-associated genes. SLE: systemic lupus erythematosus, SNP: single-nucleotide polymorphism, JAK–STAT: janus kinase–signal transducers and activators of transcription, IFN: interferon gamma. (J Rheum Dis 2024;31:200-211)

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