J Rheum Dis 2011; 18(1): 36-40
Published online March 30, 2011
© Korean College of Rheumatology
류한희ㆍ장성혜ㆍ김혜원ㆍ신기철ㆍ이은봉ㆍ임재준ㆍ송영욱
서울대학교 의과대학 서울대학교병원 내과학교실
Correspondence to : Yeong Wook Song
Caplan originally described distinctive pulmonary nodules in miners who had suffered from rheumatoid arthritis. Later, the pulmonary nodules, together with a history of rheumatoid arthritis and exposure to inorganic dust were called Caplan's syndrome. This syndrome has been described by case reports in many countries but only two cases have been reported in Korea up to now. The patient in this case report was a 70-years-old man who had worked in the construction field for 20 years mainly demolishing buildings. He was diagnosed with silicosis by a lung biopsy 1 year prior to admission. He suddenly developed arthralgia and morning stiffness in multiple joints 2 weeks prior to admission. Chest imaging revealed aggravation of the bilateral pulmonary nodules. He was diagnosed with seropositive rheumatoid arthritis. The lung nodules, arthralgia, and morning stiffness improved clinically after treatment with the corticosteroid and disease modifying anti-rheumatic drugs.
Keywords Caplan's syndrome, Rheumatoid arthritis, Pneumoconiosis, Silicosis
J Rheum Dis 2011; 18(1): 36-40
Published online March 30, 2011
Copyright © Korean College of Rheumatology.
류한희ㆍ장성혜ㆍ김혜원ㆍ신기철ㆍ이은봉ㆍ임재준ㆍ송영욱
서울대학교 의과대학 서울대학교병원 내과학교실
Han Hee Ryu, Sung Hae Chang, Hye Won Kim, Kichul Shin, Eun Bong Lee, Jae Joon Yim, Yeong Wook Song
Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
Correspondence to:Yeong Wook Song
Caplan originally described distinctive pulmonary nodules in miners who had suffered from rheumatoid arthritis. Later, the pulmonary nodules, together with a history of rheumatoid arthritis and exposure to inorganic dust were called Caplan's syndrome. This syndrome has been described by case reports in many countries but only two cases have been reported in Korea up to now. The patient in this case report was a 70-years-old man who had worked in the construction field for 20 years mainly demolishing buildings. He was diagnosed with silicosis by a lung biopsy 1 year prior to admission. He suddenly developed arthralgia and morning stiffness in multiple joints 2 weeks prior to admission. Chest imaging revealed aggravation of the bilateral pulmonary nodules. He was diagnosed with seropositive rheumatoid arthritis. The lung nodules, arthralgia, and morning stiffness improved clinically after treatment with the corticosteroid and disease modifying anti-rheumatic drugs.
Keywords: Caplan's syndrome, Rheumatoid arthritis, Pneumoconiosis, Silicosis
Roshan Subedi, M.D., Afrah Misbah, M.D., Adnan Al Najada, M.D., Anthony James Ocon, M.D., Ph.D.
J Rheum Dis -0001; ():Hee Jun Kim, R.N., Ph.D., Ju-Yang Jung, M.D., Ph.D., Ji-Won Kim, M.D., Chang-Hee Suh, M.D., Ph.D., Hyoun-Ah Kim, M.D., Ph.D.
J Rheum Dis -0001; ():In-Woon Baek, M.D., Kyung-Su Park, M.D., Ph.D., Ki-Jo Kim, M.D., Ph.D.
J Rheum Dis -0001; ():