J Rheum Dis 2011; 18(1): 50-54
Published online March 30, 2011
© Korean College of Rheumatology
황윤우ㆍ윤 환ㆍ강종식ㆍ이상아ㆍ이우제ㆍ이기업ㆍ박중열
울산대학교 의과대학 서울아산병원 내과학교실
Correspondence to : Joong Yeol Park
Necrosis of the upper extremity occurs rarely in type 2 diabetic patients compared to lower extremity necrosis. We report a 69-year-old woman with type 2 diabetes mellitus who presented with necrosis of the left 5th finger tip. The patient had primary biliary cirrhosis accompanied by necrosis of the fingertip due to severe Raynaud's phenomenon. Primary biliary cirrhosis (PBC) is a typical autoimmune disease, which can in rare cases be accompanied by autoimmune symptoms including sicca symptom and Raynaud's phenomenon. Furthermore, autoimmune diseases, such as systemic sclerosis, rheumatoid arthritis and undifferentiated connective tissue disease (UCTD) can be associated. Although every type of vascular etiology should be considered as a cause of digital necrosis, Raynaud's phenomenon is usually not considered in diabetes. We report this case of finger tip necrosis due to severe Raynaud's phenomenon accompanied by PBC and UCTD in a diabetic patient.
Keywords Primary biliary cirrhosis, Undifferentiated connective tissue disease, Raynaud's phenomenon, Necrosis, Fingers, Diabetes mellitus
J Rheum Dis 2011; 18(1): 50-54
Published online March 30, 2011
Copyright © Korean College of Rheumatology.
황윤우ㆍ윤 환ㆍ강종식ㆍ이상아ㆍ이우제ㆍ이기업ㆍ박중열
울산대학교 의과대학 서울아산병원 내과학교실
Jenie Yoonoo Hwang, Hwang Yoon, Jong Sik Kang, Sang Ah Lee, Woo Je Lee, Ki-Up Lee, Joong Yeol Park
Department of Internal Medicine, University of Ulsan College of Medicine, Seoul Asan Medical Center, Seoul, Korea
Correspondence to:Joong Yeol Park
Necrosis of the upper extremity occurs rarely in type 2 diabetic patients compared to lower extremity necrosis. We report a 69-year-old woman with type 2 diabetes mellitus who presented with necrosis of the left 5th finger tip. The patient had primary biliary cirrhosis accompanied by necrosis of the fingertip due to severe Raynaud's phenomenon. Primary biliary cirrhosis (PBC) is a typical autoimmune disease, which can in rare cases be accompanied by autoimmune symptoms including sicca symptom and Raynaud's phenomenon. Furthermore, autoimmune diseases, such as systemic sclerosis, rheumatoid arthritis and undifferentiated connective tissue disease (UCTD) can be associated. Although every type of vascular etiology should be considered as a cause of digital necrosis, Raynaud's phenomenon is usually not considered in diabetes. We report this case of finger tip necrosis due to severe Raynaud's phenomenon accompanied by PBC and UCTD in a diabetic patient.
Keywords: Primary biliary cirrhosis, Undifferentiated connective tissue disease, Raynaud's phenomenon, Necrosis, Fingers, Diabetes mellitus
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