Case Report

J Rheum Dis 2011; 18(3): 212-215

Published online September 30, 2011

© Korean College of Rheumatology

Adalimumab으로 치료한 류마티스관절염 환자에서 발생한 침습성 폐아스페르길루스증 1예

김재희ㆍ배중기ㆍ전재완ㆍ이현성ㆍ주형욱ㆍ오지선ㆍ최승원

A Case of Invasive Pulmonary Aspergillosis in a Patient with Rheumatoid Arthritis Treated with Adalimumab

Jae Hee Kim, Joong Ki Bae, Jae Wan Jun, Hyun Sung Lee, Hyung Wook Ju, Ji Seon Oh, Seung Won Choi

Department of Internal Medicine, Ulsan University Hospital, College of Medicine,University of Ulsan, Ulsan, Korea

Correspondence to : Seung Won Choi

Abstract

We describe a fatal case of invasive pulmonary aspergillosis in a patient with rheumatoid arthritis receiving the TNF-Ձ inhibitor, adalimumab. The use of TNF-Ձ inhibitor has been associated with an increased risk of infections, including tuberculosis and other opportunistic infections. Physicians should have a high index of suspicion for opportunistic infection that can develop during TNF-Ձ inhibitor treatment.

Keywords Invasive aspergillosis, Rheumatoid arthritis, Tumor necrosis factor-alpha

Article

Case Report

J Rheum Dis 2011; 18(3): 212-215

Published online September 30, 2011

Copyright © Korean College of Rheumatology.

Adalimumab으로 치료한 류마티스관절염 환자에서 발생한 침습성 폐아스페르길루스증 1예

김재희ㆍ배중기ㆍ전재완ㆍ이현성ㆍ주형욱ㆍ오지선ㆍ최승원

A Case of Invasive Pulmonary Aspergillosis in a Patient with Rheumatoid Arthritis Treated with Adalimumab

Jae Hee Kim, Joong Ki Bae, Jae Wan Jun, Hyun Sung Lee, Hyung Wook Ju, Ji Seon Oh, Seung Won Choi

Department of Internal Medicine, Ulsan University Hospital, College of Medicine,University of Ulsan, Ulsan, Korea

Correspondence to:Seung Won Choi

Abstract

We describe a fatal case of invasive pulmonary aspergillosis in a patient with rheumatoid arthritis receiving the TNF-Ձ inhibitor, adalimumab. The use of TNF-Ձ inhibitor has been associated with an increased risk of infections, including tuberculosis and other opportunistic infections. Physicians should have a high index of suspicion for opportunistic infection that can develop during TNF-Ձ inhibitor treatment.

Keywords: Invasive aspergillosis, Rheumatoid arthritis, Tumor necrosis factor-alpha

JRD
Jan 01, 2025 Vol.32 No.1, pp. 1~7
COVER PICTURE
Cumulative growth of rheumatology members and specialists (1980~2024). Cumulative distribution of the number of the (A) Korean College of Rheumatology members and (B) rheumatology specialists. (J Rheum Dis 2025;32:63-65)

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