Case Report

J Rheum Dis 2011; 18(4): 315-319

Published online December 30, 2011

© Korean College of Rheumatology

소포 림프종에 동반된 강직성 척추염 1예

박희진1ㆍ박윤혜1ㆍ박경혜1ㆍ김미현1ㆍ최은영1ㆍ한정우1ㆍ홍지영1ㆍ장명희2ㆍ김선정3ㆍ심주은4ㆍ기정혜5ㆍ이상원1ㆍ박용범1ㆍ이수곤1ㆍ이찬희2

연세대학교 의과대학 내과학교실1, 국민건강보험공단 일산병원 내과2, 핵의학과3, 영상의학과4, 병리과5

A Case of Ankylosing Spondylitis with Follicular Lymphoma

Hee Jin Park1, Yoon Hea Park1, Kyeong Hye Park1, Mihyun Kim1, Eun Yeong Choe1, Jung Woo Han1, Ji Young Hong1, Myung Hee Chang2, Sun Jung Kim3, Joo Eun Shim4, Jeong Hae Kie5, Sang-Won Lee1, Yong-Beom Park1, Soo-Kon Lee1, Chan Hee Lee2

Department of Internal Medicine, Yonsei University College of Medicine1, Seoul, Departments of Internal Medicine2, Nuclear Medicine3, Radiology4, and Pathology5, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea

Correspondence to : Chan Hee Lee

Abstract

Several autoimmune and chronic inflammatory conditions have been consistently linked with an increased risk of hematologic malignancies. Although ankylosing spondylitis (AS) is a chronic inflammatory disease, previous studies have demonstrated that it is not associated with an increase in risk of malignant lymphomas. Cases of AS accompanied by hematologic malignancies such as multiple myeloma, chronic myelogenous leukemia, and Hodgkin's disease have been reported. In Korea, AS with non- Hodgkin's lymphoma or follicular lymphoma has not been reported. We experienced a 38-year-old male who had been diagnosed with follicular lymphoma with bone metastasis, who achieved complete remission after having been treated with chemotherapy, developed new inflammatory back pain. An MRI of his hip showed an active inflammation of the left sacroiliac joint and a positive HLA-B27. The patient was diagnosed with AS and was treated with naproxen, which improved the pain in his back and buttock.

Keywords Ankylosing spondylitis, Non-Hodgkin's lymphoma, Follicular lymphoma, Inflammatory back pain

Article

Case Report

J Rheum Dis 2011; 18(4): 315-319

Published online December 30, 2011

Copyright © Korean College of Rheumatology.

소포 림프종에 동반된 강직성 척추염 1예

박희진1ㆍ박윤혜1ㆍ박경혜1ㆍ김미현1ㆍ최은영1ㆍ한정우1ㆍ홍지영1ㆍ장명희2ㆍ김선정3ㆍ심주은4ㆍ기정혜5ㆍ이상원1ㆍ박용범1ㆍ이수곤1ㆍ이찬희2

연세대학교 의과대학 내과학교실1, 국민건강보험공단 일산병원 내과2, 핵의학과3, 영상의학과4, 병리과5

A Case of Ankylosing Spondylitis with Follicular Lymphoma

Hee Jin Park1, Yoon Hea Park1, Kyeong Hye Park1, Mihyun Kim1, Eun Yeong Choe1, Jung Woo Han1, Ji Young Hong1, Myung Hee Chang2, Sun Jung Kim3, Joo Eun Shim4, Jeong Hae Kie5, Sang-Won Lee1, Yong-Beom Park1, Soo-Kon Lee1, Chan Hee Lee2

Department of Internal Medicine, Yonsei University College of Medicine1, Seoul, Departments of Internal Medicine2, Nuclear Medicine3, Radiology4, and Pathology5, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea

Correspondence to:Chan Hee Lee

Abstract

Several autoimmune and chronic inflammatory conditions have been consistently linked with an increased risk of hematologic malignancies. Although ankylosing spondylitis (AS) is a chronic inflammatory disease, previous studies have demonstrated that it is not associated with an increase in risk of malignant lymphomas. Cases of AS accompanied by hematologic malignancies such as multiple myeloma, chronic myelogenous leukemia, and Hodgkin's disease have been reported. In Korea, AS with non- Hodgkin's lymphoma or follicular lymphoma has not been reported. We experienced a 38-year-old male who had been diagnosed with follicular lymphoma with bone metastasis, who achieved complete remission after having been treated with chemotherapy, developed new inflammatory back pain. An MRI of his hip showed an active inflammation of the left sacroiliac joint and a positive HLA-B27. The patient was diagnosed with AS and was treated with naproxen, which improved the pain in his back and buttock.

Keywords: Ankylosing spondylitis, Non-Hodgkin's lymphoma, Follicular lymphoma, Inflammatory back pain

JRD
Jan 01, 2025 Vol.32 No.1, pp. 1~7
COVER PICTURE
Cumulative growth of rheumatology members and specialists (1980~2024). Cumulative distribution of the number of the (A) Korean College of Rheumatology members and (B) rheumatology specialists. (J Rheum Dis 2025;32:63-65)

Stats or Metrics

Share this article on

  • line

Related articles in JRD

Journal of Rheumatic Diseases

pISSN 2093-940X
eISSN 2233-4718
qr-code Download