J Rheum Dis 2022; 29(3): 181-186  
Pediatric Sarcoidosis Misdiagnosed as Hepatosplenic Abscesses: A Case Report and Review
Su Min Lee, M.D.1, Hyungwook Choi, M.D.2, Sungmin Lim, M.D.1, Jehee Shin, M.D.1, Ji-Man Kang, M.D., Ph.D.1,3, Jong Gyun Ahn, M.D., Ph.D.1,3
1Department of Pediatrics, Severance Children’s Hospital, Yonsei University College of Medicine, 2Department of Pathology, Severance Hospital, Yonsei University College of Medicine, 3Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Korea
Correspondence to: Jong Gyun Ahn, http://orcid.org/0000-0001-5748-0015
Department of Pediatrics, Severance Children’s Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. E-mail: JGAHN@yuhs.ac
Received: July 16, 2021; Revised: October 6, 2021; Accepted: October 23, 2021; Published online: July 1, 2022.
© Korean College of Rheumatology.

This is a open Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.
Sarcoidosis is a systemic granulomatous disorder of unknown etiology characterized by granuloma formation. Due to the limited incidence of sarcoidosis in pediatric patients, little is known about the clinical course of this disease. A combination of clinical, radiologic, and pathologic examination is necessary to exclude other differential diagnoses (i.e., infection and granulomatous inflammatory disorder) and establish a diagnosis of sarcoidosis. Here, we report a case of histologically confirmed sarcoidosis initially misdiagnosed as hepatosplenic abscesses in an 11-year-old male. Treatment with corticosteroids improved his symptoms and resolved his skin and hepatosplenic lesions. A three-year follow-up was uneventful. This study emphasizes the importance of considering sarcoidosis in children presenting with findings of multi-organ involvement in the presence of histologic evidence of granuloma.
Keywords: Sarcoidosis, Children, Granuloma, Liver abscess

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