The Journal of the Korean Rheumatism Association 2010; 17(4): 422-425
Published online December 30, 2010
© Korean College of Rheumatology
박성오ㆍ이지현
메리놀병원 류마티스내과
Correspondence to : Ji Hyun Lee
Bullous pemphigoid is an autoimmune, subepidermal blistering disease commonly seen in the elderly. It is known as autoimmune bullous dermatoses with an estimated prevalence of 1 in 40,000 and shows no gender or racial predilection. It has an autoimmune nature with immunoglobulin (Ig) G and/or C3 complement targeting hemidesmosomal antigens located in the epidermal basement membrane zone. Drug-induced pemphigoid, although rare, can occur in patients taking penicillamine, furosemide, captopril, penicillin, or sulfasalazine, but infliximab- induced pemphigoid has not been reported. We experienced a case of infliximab-induced pemphigoid in 54-year-old woman with a 17-year history of rheumatoid arthritis.
Keywords Infliximab, Bullous pemphigoid, Rheumatoid arthritis
The Journal of the Korean Rheumatism Association 2010; 17(4): 422-425
Published online December 30, 2010
Copyright © Korean College of Rheumatology.
박성오ㆍ이지현
메리놀병원 류마티스내과
Seong Oh Park, Ji Hyun Lee
Department of Rheumatology, Maryknoll Hospital, Busan, Korea
Correspondence to:Ji Hyun Lee
Bullous pemphigoid is an autoimmune, subepidermal blistering disease commonly seen in the elderly. It is known as autoimmune bullous dermatoses with an estimated prevalence of 1 in 40,000 and shows no gender or racial predilection. It has an autoimmune nature with immunoglobulin (Ig) G and/or C3 complement targeting hemidesmosomal antigens located in the epidermal basement membrane zone. Drug-induced pemphigoid, although rare, can occur in patients taking penicillamine, furosemide, captopril, penicillin, or sulfasalazine, but infliximab- induced pemphigoid has not been reported. We experienced a case of infliximab-induced pemphigoid in 54-year-old woman with a 17-year history of rheumatoid arthritis.
Keywords: Infliximab, Bullous pemphigoid, Rheumatoid arthritis
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